Protein Alignment eyg and pax3

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_012825755.1
• Gene: pax3 / 448464
• XenbaseID: XB-GENE-482740
• Length: 486
• Species: Xenopus tropicalis
• Alignment Length: 489
• Identity: 147/489 - (30%)
• Similarity: 205/489 - (41%)
• Gaps: 165/489 - (33%)

  Fly    83 PTSVQIPPGFGGGGSTGGIPHGAGGPTGSTLNTLMSQHRLLEFSRFGGLRGYDIAQHMLTQQGAV 147
            |..|..|.|.|.....||: ...|.|..:.:     :|:::|.:.. |:|...|::.:....|.|
 Frog    27 PLEVSTPLGQGRVNQLGGV-FINGRPLPNHI-----RHKIVEMAHH-GIRPCVISRQLRVSHGCV 84

  Fly   148 SKLL------GSLRPPGLIGGSKPK-VATPTVVSKIEQYKRENPTIFAWEIRERLISEGVCTNAT 205
            ||:|      ||:| ||.||||||| |.||.|..|||::||:||.:|:||||::|:.:|||...|
 Frog    85 SKILCRYQETGSIR-PGAIGGSKPKQVTTPEVEKKIEEFKRDNPGMFSWEIRDKLLKDGVCDRNT 148

  Fly   206 APSVSSINRILRNRAAE----------RVATEFARTAAYGLYPPPPHPYGSFTWHPAGNVPGGQG 260
            .||||||:||||::..:          :...|..:.|.:.:                      .|
 Frog   149 VPSVSSISRILRSKFGKGDEEDIELDRKEQEESEKRAKHSI----------------------DG 191

  Fly   261 VPPPPPPSALWSVAAPTLANLPPSAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISPGSGSHDT 325
            :.....|:                                                ||.|
 Frog   192 ILRERAPA------------------------------------------------SPES----- 203

  Fly   326 LESADENRHIDSDYLDDDDEP---KFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSL 387
                :|...|||    :.|.|   |.||:||||:.|||||||:.|:::|||.:.|||.|:.|..|
 Frog   204 ----EEGSDIDS----EPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKL 260

  Fly   388 SEARVQVWFSNRRAKWRRHQRMNLLKR----------QRSSPANPLH-----SQQSNDAPASSPT 437
            :|||||||||||||:||:....|.|..          ..:.||.|.:     |.|....|.:...
 Frog   261 TEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGAFPPAAMPALPTYQLSETSYQPTSIPQAVSD 325

  Fly   438 PSNHSSASTSAPVAPVPPP---QQPLPLCGDHSPQGPPPSVLLHPLHG---------PPGGHHHH 490
            |||     |.....|:||.   |..||    .:|:......|....||         ||.|..:
 Frog   326 PSN-----TVHRPQPLPPSSVHQSSLP----SNPESSSAYCLPSGRHGFSSYTDSFVPPSGPSN- 380

  Fly   491 HPLHLPTHPA--------ALQLLSHY----HQQQ 512
                 |.:||        .:.||:::    ||.|
 Frog   381 -----PMNPAIGNGLSPQVMGLLTNHGGVPHQPQ 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197	51/103 (50%)
		Homeodomain	349..405	CDD:459649	37/55 (67%)
pax3	XP_012825755.1	PAX	35..162	CDD:238076	59/134 (44%)
		Homeodomain	222..278	CDD:459649	37/55 (67%)
		Pax7	349..393	CDD:403540	10/49 (20%)