DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eyg and otp

DIOPT Version :9

Sequence 1:	NP_001014582.1	Gene:	eyg / 39419	FlyBaseID:	FBgn0000625	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_001286654.1	Gene:	otp / 37364	FlyBaseID:	FBgn0015524	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	117/449 - (26%)
Similarity:	169/449 - (37%)	Gaps:	176/449 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 PPSALWSVAA-----------PTLANLPPSA-----ASAVPVSTCGSLSSAHLMAGGAGGTPTN- 313
            |.:||.::.|           |.||:|...|     :..|||.  |.::..|:    :||...|
  Fly    18 PKAALTALHAGVNSFGQLPVGPNLADLGGGAGGGGSSGGVPVG--GGVARLHI----SGGLCDNS 76

  Fly   314 RAISPGSGS---------------HDTLESADENRHIDSDYLDDDDEPKFRRNRTTFSPEQLEEL 363
            .|::.|:||               :::::..|:  |:|.:        |.:|:||.|:|.||.||
  Fly    77 NALNGGNGSSGNGNGNNNNGNGNNNNSMQQQDQ--HLDKN--------KQKRHRTRFTPAQLNEL 131

  Fly   364 EKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMN--------LLKRQRSSP- 419
            |:.|.|:|||.:..||.::.|..|:|:||||||.||||||::.::..        ||......|
  Fly   132 ERCFSKTHYPDIFMREEIAMRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRTPGALLPSHGLPPF 196

  Fly   420 ---------------------------ANPL---HSQQSNDAPASSPTPS--------------- 439
                                       .||:   ..|.:..:|.||...|
  Fly   197 GANITNIAMGDGLCGTGMFGGDRWSVGVNPMTAGFGQLNQSSPLSSSLNSGLNSGINMGSALGAG 261

  Fly   440 ----------------NHSSASTS-----APVAPVPPPQQPLPLCGDHSPQGPP----PSVLLHP 479
                            .||....|     :|.|..||....   |...:|  ||    |:...:.
  Fly   262 SYQHYGLNALGDSMMYQHSVGGVSCGPSGSPSATTPPNMNS---CSSVTP--PPLSAQPNSSQNE 321

  Fly   480 LHGPPGGHHHHHPLHLPTHPAALQLLSHYHQQQQQQQQQQHQQQQ-QQHH--------QQQQQLS 535
            |:|.|      .|||                ||||||..|||||| .|||        ||||||.
  Fly   322 LNGEP------MPLH----------------QQQQQQTHQHQQQQTHQHHPMAPPTPTQQQQQLP 364

  Fly   536 PSGCNPAANHLSMGGERSAFRSLVSSPSAAAFLGLARQYAVAASLTVAEEQRSRLHYSA 594
            .|..:|:      .|......|:.:....|:.|.     |:.:.|.:|.....  ||::
  Fly   365 QSMQSPS------DGANDTLHSIAALRRRASELN-----AIPSYLQMAPHNYE--HYNS 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_001014582.1	HTH	120..217	CDD:304362
eyg	NP_001014582.1	Homeobox	352..404	CDD:278475	30/51 (59%)
otp	NP_001286654.1	Homeobox	119..167	CDD:278475	25/47 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450806
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840