DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eyg and Pph13

DIOPT Version :9

Sequence 1:	NP_001014582.1	Gene:	eyg / 39419	FlyBaseID:	FBgn0000625	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_477330.1	Gene:	Pph13 / 33239	FlyBaseID:	FBgn0023489	Length:	357	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	104/362 - (28%)
Similarity:	145/362 - (40%)	Gaps:	78/362 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 KFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMNL 411
            |.||.||||:..||:|||:.|.::|||.|..||.|:.|..|:||||||||.|||||||:.:::..
  Fly     9 KQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKIGG 73

  Fly   412 LKRQRSSPANPLHSQQSNDAPASSPTPSNHSSASTSAPVAPVPPPQQPLPL---------CGDHS 467
            |.......|..|.....:.|...    ...|:......:.|..|||....|         .|..|
  Fly    74 LGGDYKEGALDLDVSYDDSAVLG----QLDSALGGGGTLLPDTPPQSSNSLDNELKASYGTGAMS 134

  Fly   468 PQGPPPSVLLH----PLHGPPGGHHHHHPLHLPTHPAALQLLSHYHQQQQQQQQQ---------- 518
            |....|::.|:    .|....||  ....:...|:|...|..:|.......|.||
  Fly   135 PSRLSPNIFLNLNIDHLGLERGG--SGLSMEWSTYPPQTQAQTHPQMDSDNQLQQHPPQQHASDP 197

  Fly   519 ------QHQQQQQQHHQQQQQLSPSGCNPAANHLSMGGERSAFRSLVSSPSAAA-----FLGL-A 571
                  .|.|||||.|||:|.      ||   .|..|.|.:|..||..:..::|     ||.: .
  Fly   198 IHAGSSSHHQQQQQQHQQEQH------NP---QLHPGLEFAASLSLDMTDGSSAYDEMKFLSVDV 253

  Fly   572 RQYAV---AASLTVAEEQRSRLHYSAGG----LGSGGE----GTGPNTNTTQSG-----GSTMTV 620
            .|:.:   .|...::.||.....|  ||    :||..|    |.|.::...:.|     .|.:.:
  Fly   254 DQFTIDSFKADCILSMEQSQMQAY--GGHSQLVGSSNELCLDGIGMSSFGMEEGEPKSPPSLLVL 316

  Fly   621 DNS----------SSDSDEEINVHDDSDGEIESSAAT 647
            |.|          .:|..|:::.|....|.:.....|
  Fly   317 DKSLPSLSIGVEGIADLVEQLHHHQHEGGPVGGGVIT 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_001014582.1	HTH	120..217	CDD:304362
eyg	NP_001014582.1	Homeobox	352..404	CDD:278475	32/51 (63%)
Pph13	NP_477330.1	Homeobox	14..66	CDD:278475	32/51 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450818
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840