Protein Alignment eyg and pax7a

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_571400.1
• Gene: pax7a / 30587
• ZFINID: ZDB-GENE-990415-201
• Length: 507
• Species: Danio rerio
• Alignment Length: 569
• Identity: 161/569 - (28%)
• Similarity: 224/569 - (39%)
• Gaps: 181/569 - (31%)

  Fly    83 PTSVQIPPGFGGGGSTGGIPHGAGGPTGSTLNTLMSQHRLLEFSRFGGLRGYDIAQHMLTQQGAV 147
            |..|..|.|.|.....||: ...|.|..:.:     :|:::|.:.. |:|...|::.:....|.|
Zfish    26 PLEVSTPLGQGRVNQLGGV-FINGRPLPNHI-----RHKIVEMAHH-GIRPCVISRQLRVSHGCV 83

  Fly   148 SKLL------GSLRPPGLIGGSKPK-VATPTVVSKIEQYKRENPTIFAWEIRERLISEGVCTNAT 205
            ||:|      ||:| ||.||||||: ||||.|..:||:||||||.:|:||||::|:.:|||...|
Zfish    84 SKILCRYQETGSIR-PGAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRGT 147

  Fly   206 AP-----SVSSINRILRNRAAERVATEFARTAAYGLYPPPPHPYGSFTWHPAGNVPGGQGVPPPP 265
            .|     |||||:|:||.|..::...:
Zfish   148 VPSGEASSVSSISRVLRARFGKKDDDD-------------------------------------- 174

  Fly   266 PPSALWSVAAPTLANLPPSAASAVPVSTC------GSLSSAHLMAGGAGGTPTNRAISPGSGSHD 324
                                       .|      |...:.|.:.|..|               |
Zfish   175 ---------------------------ECDKKDEDGEKKTKHSIDGILG---------------D 197

  Fly   325 TLESADENRHIDSDYLDDDDEP---KFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTS 386
            .....||...::|    :.|.|   |.||:||||:.||||||||.|:::|||.:.|||.|:.||.
Zfish   198 KGNRTDEGSDVES----EPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTK 258

  Fly   387 LSEARVQVWFSNRRAKWRRHQRMNLLKRQRSSPANPLHSQQSNDAPASSPT-PSNHSSASTSAPV 450
            |:|||||||||||||:||:....|.|       |...|.......|...|| |:.....||.
Zfish   259 LTEARVQVWFSNRRARWRKQAGANQL-------AAFNHLLPGGFPPTGMPTLPTYQLPESTY--- 313

  Fly   451 APVPPPQQPLPLCGD---HSPQGPPPSVLLHPLHGPPGGHHHHHPLHLPTHPAALQLLSHYHQQQ 512
                 |...|...|.   |.||..|||.:            |...|...: .:|..|.|:.|...
Zfish   314 -----PSTTLSQDGSSTLHRPQPLPPSSM------------HQGGLSADS-GSAYGLSSNRHTFS 360

  Fly   513 QQQQQQQHQQQQQQHHQQQQQLSPSGCNPAANHLSMGGERSAFRSLVSSPSAAAFLGLARQYAVA 577
            ...:..........|           .||.:|.||     ....|::|:|||..
Zfish   361 SYSETFMSPTASSNH-----------MNPVSNGLS-----PQVMSILSNPSAVP----------- 398

  Fly   578 ASLTVAEEQRSRLHYSAGGLGSGGEGTGP-NTNTTQSGGSTMTVDNSSS 625
                 ::.|..   :|...|..|.|.:.| :.:.:|......:||:.:|
Zfish   399 -----SQPQHD---FSISPLHGGLEASNPISASCSQRSDPIKSVDSLAS 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197	51/108 (47%)
		Homeodomain	349..405	CDD:459649	39/55 (71%)
pax7a	NP_571400.1	PAX	34..166	CDD:238076	59/139 (42%)
		Homeodomain	221..277	CDD:459649	39/55 (71%)
		Pax7	343..386	CDD:403540	10/59 (17%)