Protein Alignment eyg and Otx2

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_038949211.1
• Gene: Otx2 / 305858
• RGDID: 1305705
• Length: 297
• Species: Rattus norvegicus
• Alignment Length: 316
• Identity: 80/316 - (25%)
• Similarity: 119/316 - (37%)
• Gaps: 94/316 - (29%)

  Fly   282 PPSAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISPGSGSHDTLESADENRHIDSDYLDDDDEP 346
            ||.|.:.:.::|.| :...|...|..|...:..|.:|                           .
  Rat     8 PPYAVNGLSLTTSG-MDLLHPSVGYPGPWASCPAATP---------------------------R 44

  Fly   347 KFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQR--- 408
            |.||.||||:..||:.||..|.|:.||.:..||.::.:.:|.|:||||||.|||||.|:.|:
  Rat    45 KQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ 109

  Fly   409 ---MNLLK--RQRSSPANPLHSQQSNDA----PASSPTPSNHSSASTSAPVAPVPPPQQPLPLCG 464
               .|.::  ::::|||..:.|:.....    |:|:..|   :.||:||||:...|..
  Rat   110 NGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVP---TIASSSAPVSIWSPAS------- 164

  Fly   465 DHSPQGPPPSVLLHPLHGPPGGHHHHHPLHLPTHPAALQLLSHYHQQQQQQQQQQHQQQQQ---- 525
                        :.||..|           |.|..:.:|........|.....|.:.....
  Rat   165 ------------ISPLSDP-----------LSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGG 206

  Fly   526 ---------QHHQ---QQQQLSPSGCNPAANHLSMGGERSAFRSLVSSPSAAAFLG 569
                     .|||   ....|||.|.|...:||:...     .||.:....|:.||
  Rat   207 MDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSP-----ASLSTQGYGASSLG 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197
		Homeodomain	349..405	CDD:459649	29/55 (53%)
Otx2	XP_038949211.1	Homeodomain	47..102	CDD:459649	29/54 (54%)
		TF_Otx	161..242	CDD:427350	19/110 (17%)