Protein Alignment eyg and pax3a

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_571352.1
• Gene: pax3a / 30532
• ZFINID: ZDB-GENE-980526-52
• Length: 509
• Species: Danio rerio
• Alignment Length: 632
• Identity: 172/632 - (27%)
• Similarity: 235/632 - (37%)
• Gaps: 235/632 - (37%)

  Fly    71 AVAGG---------------GGATSTSPTSVQIPPGFGGGGSTGGIPHGAGGPTGSTLNTLMSQH 120
            |:|||               ||.:    ..|..|.|.|.....||: ...|.|..:.:     :|
Zfish     3 ALAGGISRMMRPTPPQNYPRGGYS----LEVSTPLGQGRVNQLGGV-FINGRPLPNHI-----RH 57

  Fly   121 RLLEFSRFGGLRGYDIAQHMLTQQGAVSKLL------GSLRPPGLIGGSKPKVA-TPTVVSKIEQ 178
            :::|.:.. |:|...|::.:....|.|||:|      ||:| ||.|||||||.: ||.|..|||:
Zfish    58 KIVEMAHH-GIRPCVISRQLRVSHGCVSKILCRYQETGSIR-PGAIGGSKPKQSTTPDVEKKIEE 120

  Fly   179 YKRENPTIFAWEIRERLISEGVCTNATAPSVSSINRILR-------------NRAAERVATEFAR 230
            ||||||.:|:||||::|:.:|:|.....||||||:|:||             :...:|...|..|
Zfish   121 YKRENPGMFSWEIRDKLLKDGICDRNNVPSVSSISRMLRCKFGGNGDEDEDDDEVEKREIEENER 185

  Fly   231 TAAYGLYPPPPHPYGSFTWHPAGNVPGGQGVPPPPPPSALWSVAAPTLANLPPSAASAVPVSTCG 295
            .|.                |....:.|.:
Zfish   186 RAK----------------HSIDGILGDR------------------------------------ 198

  Fly   296 SLSSAHLMAGGAGGTPTNRAISPGSGSHDTLESADENRHIDSDYLDDDDEP------KFRRNRTT 354
               |:|                           :||...:||       ||      |.||:|||
Zfish   199 ---SSH---------------------------SDEGSDVDS-------EPGLPLKRKQRRSRTT 226

  Fly   355 FSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMN-LLKRQRSS 418
            |:.|||||||:.|:::|||.:.|||.|:.|..|:|||||||||||||:||:....| |:......
Zfish   227 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLI 291

  Fly   419 PANPLHSQQSNDAP---ASSPTPSNHSSASTSAPVAPVPPPQQPLPLCGDH---------SPQGP 471
            |.....|..|:..|   |.||.|.:..|..:..|.....|  ||||....|         :.:|.
Zfish   292 PGGFPPSAMSSLQPYQLADSPYPPSSISQVSEQPSTVHRP--QPLPPTSVHQSGLGSGPGAQEGS 354

  Fly   472 PPSVLLHPLHG----------PPGGHHHHHPLH------LPT------HPAALQLLSHYHQQQQQ 514
            ....|....||          .||   |.:|::      ||:      :|.|:.
Zfish   355 SAYCLSSGRHGFSGYSDGYVAAPG---HANPVNPSISNGLPSQVMGLLNPGAVP----------- 405

  Fly   515 QQQQQHQQQQQQHHQQQQQ---------LSPSGCNPAANHLSMGGERSAFRSLVSSPSAAAFLGL 570
                         ||.|..         |.||...||:.|              ||....|..||
Zfish   406 -------------HQPQSDFALSPLTGGLEPSTGMPASCH--------------SSQRLEALPGL 443

  Fly   571 ARQYAVAASLTVAEEQRSRLHYSAGGLGS------GGEGTGPNTNTT 611
            ....|:.:|.:......|...||...:.|      |......:|.||
Zfish   444 PSMPALPSSQSYCPSSYSSPGYSVDHVASYQYSQYGQSKVNTSTVTT 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197	49/103 (48%)
		Homeodomain	349..405	CDD:459649	37/55 (67%)
pax3a	NP_571352.1	PAX	34..159	CDD:128645	55/132 (42%)
		Homeodomain	221..277	CDD:459649	37/55 (67%)
		Pax7	350..394	CDD:403540	10/46 (22%)