Protein Alignment eyg and rx2

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_571301.2
• Gene: rx2 / 30473
• ZFINID: ZDB-GENE-990415-237
• Length: 327
• Species: Danio rerio
• Alignment Length: 277
• Identity: 85/277 - (30%)
• Similarity: 115/277 - (41%)
• Gaps: 80/277 - (28%)

  Fly   323 HDT---------LESADENRHIDSDY----LDDDDEP--KFRRNRTTFSPEQLEELEKEFDKSHY 372
            |||         .:..|...:::||.    :.|:|:|  |.|||||||:..||.|||:.|:||||
Zfish    95 HDTGLFSTDKCDADLGDPRSNVESDSRSPDIPDEDQPKKKHRRNRTTFTTYQLHELERAFEKSHY 159

  Fly   373 PCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMNLLKRQRSSPANPLHSQQSNDAPASSPT 437
            |.|.:||.|:.:.:|.|.||||||.||||||||.::|:       :....||     |:|..|
Zfish   160 PDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKMD-------TGTMKLH-----DSPIRS-- 210

  Fly   438 PSNHSSASTSAPVAP-VPPPQQPLPLCGDHSPQGPPPSVLLHPLHGPPG----GH-----HHHHP 492
                   ....|:|| |.|....|||    .|....|.....|:|..||    |.     :..||
Zfish   211 -------FNRPPMAPNVGPMSNSLPL----DPWLSSPLSSATPMHSIPGFMGPGQSLQPTYTAHP 264

  Fly   493 LHLPTHPAALQLLSHYHQQQQQQQQQQHQQQQQQHHQQQQQLSPSGCNPAANHLSMGGERSAFRS 557
            ..|.|.|..:|                        :.|.....|..|.|..|      ::.....
Zfish   265 GFLNTSPGMMQ------------------------NMQPMPPPPYQCQPVFN------DKYPLED 299

  Fly   558 LVSSPSAAAFLGLARQY 574
            :..|.|.||....|:::
Zfish   300 VDRSSSIAALRMKAKEH 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197
		Homeodomain	349..405	CDD:459649	36/55 (65%)
rx2	NP_571301.2	Octapeptide motif	37..44
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..73
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	100..139		9/38 (24%)
		Homeodomain	136..192	CDD:459649	36/55 (65%)
		OAR	302..316	CDD:461067	5/13 (38%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	304..317		4/13 (31%)
		Nuclear localization signal. /evidence=ECO:0000255	310..314		0/3 (0%)