DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eyg and Mixl1

DIOPT Version :9

Sequence 1:	NP_001014582.1	Gene:	eyg / 39419	FlyBaseID:	FBgn0000625	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_001099449.1	Gene:	Mixl1 / 289311	RGDID:	1310011	Length:	231	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	73/251 - (29%)
Similarity:	95/251 - (37%)	Gaps:	73/251 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 AAERVATEFARTAAYGLYPPPPHPYGSFTWHPAGN-VPGGQ---GVPPPPPPSALWSVAAPTLAN 280
            ||.....:||..||:..:|..         ||.|. :|..:   |:||.||.|.. ..|.|...:
  Rat     3 AAGSQQLQFAEGAAFPTFPAA---------HPGGQLLPAARPATGLPPAPPDSRA-PAATPCFPS 57

  Fly   281 LPPSAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISPGSGSHDTLESADENRHIDSDYLDDDDE 345
            ..|..|:..|                .|..|      ||........||.:
  Rat    58 RGPRPAAQTP----------------TGLDP------PGPSKGSAAPSAPQ-------------- 86

  Fly   346 PKFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMN 410
               ||.||:||.|||:.||..|.::.||.:..||||::.|.|.|:|:||||.|||||.|
  Rat    87 ---RRKRTSFSSEQLQLLELVFRQTMYPDIHLRERLAALTLLPESRIQVWFQNRRAKSR------ 142

  Fly   411 LLKRQRSSPANPLHSQQSNDAPASSPTPSNHSSASTSAPVAPVPPPQQPLPLCGDH 466
               ||......||.|::.:.  ...|.|...         |....||.||....:|
  Rat   143 ---RQSGKSFQPLSSRREDF--LHRPAPGTE---------ARCLKPQLPLEADVNH 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_001014582.1	HTH	120..217	CDD:304362
eyg	NP_001014582.1	Homeobox	352..404	CDD:278475	29/51 (57%)
Mixl1	NP_001099449.1	PRK14971	<2..139	CDD:237874	56/184 (30%)
Mixl1	NP_001099449.1	Homeobox	89..143	CDD:395001	30/62 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810