DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eyg and Duxbl1

DIOPT Version :9

Sequence 1:	NP_001014582.1	Gene:	eyg / 39419	FlyBaseID:	FBgn0000625	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_899245.1	Gene:	Duxbl1 / 278672	MGIID:	1916048	Length:	350	Species:	Mus musculus

Alignment Length:	185	Identity:	56/185 - (30%)
Similarity:	86/185 - (46%)	Gaps:	38/185 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 DDDEPKF---RRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKW 403
            :.|:|:.   ||:||.|:..|.:.|.:.|:|:.:|.:.|||:|:.:|.:.|:|:.:||.||||
Mouse    85 EQDKPRVKEARRSRTHFTKFQTDILIEAFEKNRFPGIVTREKLAQQTGIPESRIHIWFQNRRA-- 147

  Fly   404 RRHQRMNLLKRQRSSPANPLHSQQSNDAPAS------SPTPSNHSSASTSAPVAPVPPPQQPLPL 462
             ||....  :..:.:|    |..||:..|..      :|:.:..||||...|::|...|..||.|
Mouse   148 -RHPDPG--QNTQKTP----HPPQSSQGPTQKTVGKLAPSKTLTSSASVILPLSPPHTPNGPLDL 205

  Fly   463 CGDHSPQGPPPSVL------------LHPLHG------PPG--GHHHHHPLHLPT 497
            ......|.|..::|            .:|..|      .||  |.|...||.|.|
Mouse   206 SKGRQKQLPGTTLLQSSQVVQQRSDDQNPNKGHLSPTTTPGEQGFHSQPPLQLLT 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_001014582.1	HTH	120..217	CDD:304362
eyg	NP_001014582.1	Homeobox	352..404	CDD:278475	21/51 (41%)
Duxbl1	NP_899245.1	homeodomain	15..71	CDD:238039
Duxbl1	NP_899245.1	HOX	95..149	CDD:197696	23/56 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810