Protein Alignment eyg and OTP

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_115485.1
• Gene: OTP / 23440
• HGNCID: 8518
• Length: 325
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 83/295 - (28%)
• Similarity: 115/295 - (38%)
• Gaps: 103/295 - (34%)

  Fly   253 GNVPGGQGVPPPPPPSALWSVAAPTLANLPPSAASAVP---VSTCGSLSSAHLMAGGAGGTPTNR 314
            |:.|||.       |..|    ||.  :.|...|:.:|   ::|.||             ||.:.
Human    35 GSDPGGH-------PGDL----APN--SDPVEGATLLPGEDITTVGS-------------TPASL 73

  Fly   315 AIS-------PGSGSHDTLESADENRHIDSDYLDDDDEPKFRRNRTTFSPEQLEELEKEFDKSHY 372
            |:|       ||.........|.:.:          .:.|.:|:||.|:|.||.|||:.|.|:||
Human    74 AVSAKDPDKQPGPQGGPNPSQAGQQQ----------GQQKQKRHRTRFTPAQLNELERSFAKTHY 128

  Fly   373 PCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMNLLKRQRSSPANPLHSQQSNDAPAS-SP 436
            |.:..||.|:.|..|:|:||||||.||||||::.::...:.|                ||.: .|
Human   129 PDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFR----------------APGTLLP 177

  Fly   437 TPS--NHSSASTSAPVA--------------------------PVPPP-------QQPLPLCGDH 466
            ||.  ...||:.:|..|                          |:||.       .|.|..|.
Human   178 TPGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCS-- 240

  Fly   467 SPQGPPPSV--LLHPLHGPPGGHHHHHPLHLPTHP 499
            ...||||:.  |.:.|.|..|.....| |:.|..|
Human   241 LAAGPPPNSMGLSNSLAGSNGAGLQSH-LYQPAFP 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197
		Homeodomain	349..405	CDD:459649	33/55 (60%)
OTP	NP_115485.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..112		25/112 (22%)
		Homeodomain	106..156	CDD:459649	28/49 (57%)
		OAR	303..320	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	306..319