Protein Alignment eyg and Otx2

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001273410.1
• Gene: Otx2 / 18424
• MGIID: 97451
• Length: 297
• Species: Mus musculus
• Alignment Length: 313
• Identity: 80/313 - (25%)
• Similarity: 119/313 - (38%)
• Gaps: 88/313 - (28%)

  Fly   282 PPSAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISPGSGSHDTLESADENRHIDSDYLDDDDEP 346
            ||.|.:.:.::|.| :...|...|..|...:..|.:|                           .
Mouse     8 PPYAVNGLSLTTSG-MDLLHPSVGYPGPWASCPAATP---------------------------R 44

  Fly   347 KFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQR--- 408
            |.||.||||:..||:.||..|.|:.||.:..||.::.:.:|.|:||||||.|||||.|:.|:
Mouse    45 KQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ 109

  Fly   409 ---MNLLK--RQRSSPANPLHSQQSNDAPASSPTPSN-HSSASTSAPVAPVPPPQQPLPLCGDHS 467
               .|.::  :::||||..:.|:.......|.|:.:: .:.||:||||:...|..
Mouse   110 NGGQNKVRPAKKKSSPAREVSSESGTSGQFSPPSSTSVPTIASSSAPVSIWSPAS---------- 164

  Fly   468 PQGPPPSVLLHPLHGPPGGHHHHHPLHLPTHPAALQLLSHYHQQQQQQQQQQHQQQQQ------- 525
                     :.||..|           |.|..:.:|........|.....|.:.....
Mouse   165 ---------ISPLSDP-----------LSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDC 209

  Fly   526 ------QHHQ---QQQQLSPSGCNPAANHLSMGGERSAFRSLVSSPSAAAFLG 569
                  .|||   ....|||.|.|...:||:...     .||.:....|:.||
Mouse   210 GSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSP-----ASLSTQGYGASSLG 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197
		Homeodomain	349..405	CDD:459649	29/55 (53%)
Otx2	NP_001273410.1	Homeodomain	47..102	CDD:459649	29/54 (54%)
		TF_Otx	161..242	CDD:427350	19/110 (17%)