Protein Alignment eyg and Prrx2

DIOPT Version :10

• Sequence 1: NP_524042.2
• Gene: eyg / 39419
• FlyBaseID: FBgn0000625
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001402085.1
• Gene: Prrx2 / 113931
• RGDID: 1311471
• Length: 248
• Species: Rattus norvegicus
• Alignment Length: 303
• Identity: 90/303 - (29%)
• Similarity: 129/303 - (42%)
• Gaps: 88/303 - (29%)

  Fly   232 AAYGLYPPPPHPYGSFTWHPAGNVPGGQGVPPPPPP----SALWSVAAPTLANLPPSAASAVPVS 292
            ||:.|.||.|.|                  .|||.|    .|..:.:...|.:|...||:.  ..
  Rat     6 AAFALDPPAPGP------------------GPPPAPGDCAQARKNFSVSHLLDLEEVAAAG--RR 50

  Fly   293 TCGSLSSAHLMAGGA----GGTPTNRAI-------SPGSGSHDTLESADENRHIDSDYLDDDDEP 346
            ..|.:.......|.|    ||:..:.|.       |||.|      ||.:.:            .
  Rat    51 AAGPVPGPEAREGAAREPSGGSSGSEAAPQDGDCPSPGHG------SATKRK------------K 97

  Fly   347 KFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWFSNRRAKWRRHQRMNL 411
            |.|||||||:..||:.||:.|:::|||....||.|:.|.:||||||||||.|||||:||::|..|
  Rat    98 KQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAML 162

  Fly   412 LKRQRSSPANPLHSQQSNDAPASSPTPS----NHSSASTSAPVAPVPPPQQPLPLCGDHSPQGPP 472
            ..|..|...:  :.|::......:|.|:    ::.|...|:|.:.|||          :||.|..
  Rat   163 ATRSASLLKS--YGQEAAIEQPVAPRPTTLSPDYLSWPASSPYSSVPP----------YSPGGSS 215

  Fly   473 PSVLLHPLHGPPGGHHHHHPLHLPTHPAALQL----LSHYHQQ 511
            |:.        ||       :::....|:|:|    .|.:|.|
  Rat   216 PAT--------PG-------VNMANSIASLRLKAKEFSLHHSQ 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eyg	NP_524042.2	HTH_ARSR	120..217	CDD:481197
		Homeodomain	349..405	CDD:459649	34/55 (62%)
Prrx2	NP_001402085.1	Homeodomain	104..156	CDD:459649	30/51 (59%)
		COG5576	<110..214	CDD:227863	44/115 (38%)
		OAR	222..238	CDD:461067	3/15 (20%)