Protein Alignment toe and Pax4

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_113987.1
• Gene: Pax4 / 83630
• RGDID: 620433
• Length: 349
• Species: Rattus norvegicus
• Alignment Length: 467
• Identity: 133/467 - (28%)
• Similarity: 185/467 - (39%)
• Gaps: 162/467 - (34%)

  Fly   104 LGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYDLAQHMLSQQGAVSKLL---- 164
            |||:|..|...              .|.::.::::|:..|:|..|:::.:....|.|||:|
  Rat    12 LGGLFVNGRPL--------------PLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYY 62

  Fly   165 --GTLRPPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLITEGVCTNATAPSVSSINR 227
              |.|.|.| ||||||::|||.||::|.|.|.|.|.:|||||:.:|..||:||...|||||||||
  Rat    63 RTGVLEPKG-IGGSKPRLATPAVVARIAQLKDEYPALFAWEIQRQLCAEGLCTQDKAPSVSSINR 126

  Fly   228 ILRNRAAERAAAEFARAASYGYAIHPTHPHPYTSFPTWPAHHPLWGAVPLATPPGGGPAGAGGAL 292
            :|      ||..|..|       :|.|.                     |.:|....||
  Rat   127 VL------RALQEDQR-------LHWTQ---------------------LRSPAVLAPA------ 151

  Fly   293 QPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSR 357
                                                               ||  ||.|.....|
  Rat   152 ---------------------------------------------------LP--SPHSNCEAPR 163

  Fly   358 SPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTA 422
            .|....:                    .||||.|||.|.:.|||||.:..||....|.||||.|:
  Rat   164 GPHPGTS--------------------HRNRTIFSPGQAEALEKEFQRGQYPDSVVRGKLAAATS 208

  Fly   423 LSEARVQVWFSNRRAKWRRHQRV-----------NLIKQRDSP---STSSSPTPLVN---PVVSP 470
            |.|..|:||||||||||||.:::           :|:..:|||   |...||..:.:   ||:..
  Rat   209 LPEDTVRVWFSNRRAKWRRQEKLKWETQMPGASQDLMVPKDSPGIISAQQSPGSVPSAALPVLEQ 273

  Fly   471 VSPI-------PVPVPVAVPESGQQ-KQPYPYSTSNMCNTSSSS--SNSQPCNTINPGSKMSSKT 525
            ::|.       .||...:...:.|. .||| :...::...:|||  ..:.||.|.:|...:....
  Rat   274 LNPSFCQLCWGAVPDRCSSDTTSQACLQPY-WECHSLLPVASSSYMEFAWPCLTTHPVHHLIGGP 337

  Fly   526 SSVSSNQHMEEP 537
            ....|..::..|
  Rat   338 GQAPSTYYLHWP 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	48/101 (48%)
		Homeobox	388..440	CDD:278475	31/51 (61%)
Pax4	NP_113987.1	PAX	5..129	CDD:128645	55/137 (40%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	8..64		15/65 (23%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	83..131		28/53 (53%)
		Homeobox	174..226	CDD:278475	31/51 (61%)
		Transcription repression	278..349		14/71 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810