DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment toe and cdx4

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_571184.2	Gene:	cdx4 / 798281	ZFINID:	ZDB-GENE-980526-330	Length:	270	Species:	Danio rerio

Alignment Length:	240	Identity:	68/240 - (28%)
Similarity:	92/240 - (38%)	Gaps:	48/240 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 PHPYTSFPTWP----AHH-----------PLWGAVPLATPPGGGPAGAGGALQPGGSGSSYGSDG 305
            |..:.|.|.:.    .||           ..|||      |.|.|....||...|...|......
Zfish    28 PQNFVSTPQYSDFTGYHHVPNMETHAQSAGAWGA------PYGAPREDWGAYSLGPPNSISAPMS 86

  Fly   306 NMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIE 370
            |.|..|.|     ..|..:||..|.|..........:.:..|||:...|:|            .:
Zfish    87 NSSPGPVS-----YCSPDYNTMHGPGSAVLPPPPENIPVAQLSPERERRNS------------YQ 134

  Fly   371 GEDSESQDSDQPKFR---RNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWF 432
            ......|.|...|.|   :.|..::..|..||||||..:.|..:..:.:||....|||.:|::||
Zfish   135 WMSKTVQSSSTGKTRTKEKYRVVYTDHQRLELEKEFHFNRYITIRRKSELAVNLGLSERQVKIWF 199

  Fly   433 SNRRAKWRRHQRVNLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVP 477
            .|||||.|:     |||::...|..|..:...:|  ..|||:|||
Zfish   200 QNRRAKERK-----LIKKKLGQSDGSGGSVHSDP--GSVSPLPVP 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	22/51 (43%)
cdx4	NP_571184.2	Caudal_act	15..138	CDD:282574	29/132 (22%)
cdx4	NP_571184.2	Homeobox	155..207	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910