DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment toe and phox2ba

DIOPT Version :9

Sequence 1:NP_524041.2 Gene:toe / 39418 FlyBaseID:FBgn0036285 Length:640 Species:Drosophila melanogaster
Sequence 2:NP_001139175.1 Gene:phox2ba / 795258 ZFINID:ZDB-GENE-090313-51 Length:155 Species:Danio rerio


Alignment Length:148 Identity:54/148 - (36%)
Similarity:71/148 - (47%) Gaps:23/148 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   380 DQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQR 444
            ::.|.||.||.|:..||..||:.|..:.||.:.|||:|.....|:||||||||.|||||:|:.:|
Zfish     9 ERRKQRRVRTIFTSAQLKALERAFAHTQYPDIYTREELVQEIQLTEARVQVWFQNRRAKFRKQER 73

  Fly   445 V-----NLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVPVAVPESGQQKQ-----PYPYSTSNM 499
            .     :..|...|||..||.|.   ....|.|..|     ::|..|.|||     |.|.....:
Zfish    74 AASWNESSSKTHSSPSHDSSETA---SATDPDSTQP-----SLPLIGDQKQDSRDRPPPEELPLL 130

  Fly   500 CNTSSSSSNSQ-----PC 512
            ...:|..:..|     ||
Zfish   131 LGLTSLEAQRQRGHQIPC 148

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
toeNP_524041.2 HTH 134..230 CDD:304362
Homeobox 388..440 CDD:278475 28/51 (55%)
phox2baNP_001139175.1 Homeobox 17..69 CDD:278475 28/51 (55%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000011
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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