DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and Rhox13

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001171931.1	Gene:	Rhox13 / 73614	MGIID:	1920864	Length:	232	Species:	Mus musculus

Alignment Length:	180	Identity:	46/180 - (25%)
Similarity:	88/180 - (48%)	Gaps:	8/180 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   273 GAVPLATPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNS-SNSNTTHSNGHNTNSGSGCGDSS 336
            |||.:|.........:|||:   |..:...|:.:..|..:| |.|:::.|:..:.:..|...:.:
Mouse    39 GAVEVAQAAVASSHDSGGAI---GCATVKESESDSESESDSESESDSSDSSDESDDDSSTSDEDT 100

  Fly   337 AGSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQPKFRRNRTT--FSPEQLDEL 399
            :.....:.|:::..:.:  :..|...|...|.|.|...........:.||....  |:..|::|:
Mouse   101 SDPEEAAAPSVAAVAAA--AAPPTVPAAAAIQIPGPYRYRPPRRHVRRRRRGPPFHFAQWQVEEM 163

  Fly   400 EKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIK 449
            |..|:::.||.:.||.:||....:.|.:|:|||:|||||.|:.:|..:::
Mouse   164 ESLFEETQYPDLLTRGELARTLNVPEVKVKVWFTNRRAKQRKIERREMLR 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	21/53 (40%)
Rhox13	NP_001171931.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..114		12/71 (17%)
Rhox13	NP_001171931.1	Homeobox	155..204	CDD:278475	21/48 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910