DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment toe and vox

DIOPT Version :9

Sequence 1:NP_524041.2 Gene:toe / 39418 FlyBaseID:FBgn0036285 Length:640 Species:Drosophila melanogaster
Sequence 2:NP_571773.1 Gene:vox / 64807 ZFINID:ZDB-GENE-010108-1 Length:242 Species:Danio rerio


Alignment Length:155 Identity:49/155 - (31%)
Similarity:72/155 - (46%) Gaps:28/155 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   343 SLPALSPDSGSRDSRSPDADANRMIDIE-GEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKS 406
            |.|:.|.:||.......:|.|:....:| |.|:|...:.    ||.||.|:|||:|:|||.|:|.
Zfish    79 SSPSFSENSGYSSGYESEAAASECASVEDGHDAEKDGAT----RRIRTKFTPEQIDKLEKIFNKH 139

  Fly   407 HYPCVNTREKLAARTALSEARVQVWFSNRRAKWRR---HQRVNLIKQRDSPSTSSSPTPLVNPVV 468
            .|.....|.|.|.:..|||.:::.||.|||.|.:|   ..|.:.:              |...|:
Zfish   140 KYLDAGERVKTALKLGLSETQIRTWFQNRRMKLKREVQEMRADFL--------------LPQMVL 190

  Fly   469 SPVSPIPVPVPVAVPESGQQKQPYP 493
            .||      :||......:|:.|:|
Zfish   191 PPV------IPVQYQCYDRQRLPFP 209

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
toeNP_524041.2 HTH 134..230 CDD:304362
Homeobox 388..440 CDD:278475 25/51 (49%)
voxNP_571773.1 COG5576 75..>187 CDD:227863 41/125 (33%)
Homeobox 121..173 CDD:278475 25/51 (49%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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