DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment toe and SDCBP

DIOPT Version :9

Sequence 1:NP_524041.2 Gene:toe / 39418 FlyBaseID:FBgn0036285 Length:640 Species:Drosophila melanogaster
Sequence 2:NP_001335270.1 Gene:SDCBP / 6386 HGNCID:10662 Length:319 Species:Homo sapiens


Alignment Length:84 Identity:21/84 - (25%)
Similarity:36/84 - (42%) Gaps:9/84 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 PSTPILTQGAPPAAALGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSR---FGLRGYDLA 150
            |....:|........:|.||..|...:....::||.   |.|.::|.:.|::.   .||:...:|
Human   215 PFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAAR---NGLLTEHNICEINGQNVIGLKDSQIA 276

  Fly   151 QHMLSQQGAVSKLLGTLRP 169
            . :||..|.|..:  |:.|
Human   277 D-ILSTSGTVVTI--TIMP 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
toeNP_524041.2 HTH 134..230 CDD:304362 11/39 (28%)
Homeobox 388..440 CDD:278475
SDCBPNP_001335270.1 PDZ_signaling 133..212 CDD:238492
PDZ_signaling 217..290 CDD:238492 18/78 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0849
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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