Protein Alignment toe and pax8

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_001339893.5
• Gene: pax8 / 60637
• ZFINID: ZDB-GENE-001030-3
• Length: 448
• Species: Danio rerio
• Alignment Length: 519
• Identity: 137/519 - (26%)
• Similarity: 203/519 - (39%)
• Gaps: 142/519 - (27%)

  Fly   104 LGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYDLAQHMLSQQGAVSKLLGTLR 168
            |||:|..|..             |..:..| |:::::..|:|..|:::.:....|.|||:||...
Zfish    15 LGGMFVNGRP-------------LPEVIRQ-RIVDMAHQGVRPCDISRQLRVSHGCVSKILGRYY 65

  Fly   169 -----PPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLITEGVCTNATAPSVSSINRI 228
                 .||:|||||||||||.||.||.:|||:|||:||||||:||:.||||...|.|||||||||
Zfish    66 ETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDGDTVPSVSSINRI 130

  Fly   229 LRNRAAERAAAEF-ARAASYGYAIHPTHPHPYTSFPTWPAHHPLWGAVPLATPPGGGPAGAGGAL 292
            :|.:..:...... .:..|.|:.:.|:                  .||   |||        .:.
Zfish   131 IRTKVQQPFNLPLDTKGLSPGHTLIPS------------------SAV---TPP--------ESP 166

  Fly   293 QPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDS--SAGSGRLSLPALSPDSGSRD 355
            |....||:|..:|.:.....:::.    ..||:.:....|..|  |.|||          .|:|.
Zfish   167 QSDSLGSTYSINGLLGITQTTADG----KRGHDDSDQESCRHSVDSQGSG----------GGARK 217

  Fly   356 SRSPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAAR 420
            ....:...:..:|...|...|.||           ||       :.:.::..||..      ...
Zfish   218 QLRTEHFPSAALDCGFERHYSSDS-----------FS-------QSKAEQQLYPLA------LMN 258

  Fly   421 TALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSSSPTPL-----VNPVVSPVSPIPVPVPV 480
            ..|.|.:.....|...|   .||...::.:      :..|.||     |:|.|:.:||
Zfish   259 PGLDEGKGASSISRNLA---AHQGYAVVTE------ALQPLPLCLKQEVSPEVNSLSP------- 307

  Fly   481 AVPESGQQKQPYPYSTSNMCNTSSSSSNSQPCNTINPGSKMSSKTSSVSSNQHMEEPAAAVATAS 545
                     .|:..|.|...:.|:.||.|            |:..:|...:.|:....::.:..:
Zfish   308 ---------SPHIISGSAFLDLSAISSPS------------SAPVASSCGSAHLSHGFSSFSHHA 351

  Fly   546 PT---ASAPLSMGGENSAFRALPMTLPMPMTLPTASAAAFALSFARQYIAKYMGTPLNLGHGSS 606
            |.   .|:|..|.|...|...||   ..|..:|||..     .|:...||..:..|...|...|
Zfish   352 PVHGQFSSPSLMAGREVASSMLP---GYPPHIPTAQT-----GFSSSTIAGMVSAPEYTGQSYS 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	55/100 (55%)
		Homeobox	388..440	CDD:278475	8/51 (16%)
pax8	XP_001339893.5	PAX	8..132	CDD:128645	62/130 (48%)
		Pax2_C	343..437	CDD:289189	18/73 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810