DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and AgaP_AGAP012428

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_001688571.1	Gene:	AgaP_AGAP012428 / 5668381	VectorBaseID:	AGAP012428	Length:	279	Species:	Anopheles gambiae

Alignment Length:	324	Identity:	79/324 - (24%)
Similarity:	118/324 - (36%)	Gaps:	95/324 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 DADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALS 424
            |.|.|.:.:..|..|.|..|  .|.|:.||.|:..||..|||.|::..|..|..|.:||.:..||
Mosquito     3 DEDGNSIKNGLGLSSSSGLS--KKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLGLS 65

  Fly   425 EARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSS---------------SPTPLVNPVVSPVS-- 472
            :.:|:.|:.|||.||:|...|.|....::.:.::               .|||...|..|..:
Mosquito    66 DTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGPPYIGAWPYPTPSGPPGTSQSAVD 130

  Fly   473 --------------PIPVPVPVAVPESGQ------QKQPYPY-STSNMCNTSSS----SSNSQPC 512
                          |:|..:...||..|.      ...|:|: |.|:..:|.||    :...||.
Mosquito   131 AYYRHAAAAAALQKPLPYRMYPGVPTIGTLNPISGPSGPFPHLSASSSLSTLSSYYQANCGQQPA 195

  Fly   513 NTINPGSKMSSKTSSVSSNQHMEEPAAAVATASP------TASAPLSMGGENSAFRALPMTLPMP 571
            .::   .:...:|.|..||| :.:...:|...|.      .:...:|....||..|    ..|.|
Mosquito   196 GSL---LQQPHQTPSGGSNQ-LRDGETSVGAGSQHDISNLNSLTSISNHSLNSQIR----HSPSP 252

  Fly   572 MTLPTASAAAFALSFARQYIAKYMGTPLNLGHGSSPIQAQSGRDHQSEEREYEDEQEEEEVINV 635
            |..|                            ||.|.|::|..         .|..:||:.|.|
Mosquito   253 MLNP----------------------------GSPPGQSESNP---------PDSDDEEDNIQV 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	22/51 (43%)
AgaP_AGAP012428	XP_001688571.1	Homeobox	29..81	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910