Protein Alignment toe and pax7b

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001139621.1
• Gene: pax7b / 566533
• ZFINID: ZDB-GENE-080917-54
• Length: 510
• Species: Danio rerio
• Alignment Length: 676
• Identity: 176/676 - (26%)
• Similarity: 259/676 - (38%)
• Gaps: 250/676 - (36%)

  Fly    19 SLPGAAPAIPATATAGSQSPGAIMPMAAVPLPSHLQLLGSSAGGVGQPAAITPVSPTAATTVLAQ 83
            ||||..|.:...|      ||...|....|
Zfish     3 SLPGTVPRMMRPA------PGQNYPRTGFP----------------------------------- 26

  Fly    84 PHSLSPSTPILTQGAPPAAALGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYD 148
               |..|||:   |......|||:|..|....            |.:  :|:::|::..|:|...
Zfish    27 ---LEVSTPL---GQGRVNQLGGVFINGRPLP------------NHI--RHKIVEMAHHGIRPCV 71

  Fly   149 LAQHMLSQQGAVSKLL------GTLRPPGLIGGSKPK-----VATPTVVSKIEQYKRENPTIFAW 202
            :::.:....|.|||:|      |::| ||.||||||:     ||||.|..:||:||||||.:|:|
Zfish    72 ISRQLRVSHGCVSKILCRYQETGSIR-PGAIGGSKPRQTQKQVATPDVEKRIEEYKRENPGMFSW 135

  Fly   203 EIRERLITEGVCTNATAP-----SVSSINRILRNRAAERAAAEFARAASYGYAIHPTHPHPYTSF 262
            |||::|:.:|||..:|.|     |||||:|:||.|..::
Zfish   136 EIRDKLLKDGVCDRSTVPSGEASSVSSISRVLRARFGKK-------------------------- 174

  Fly   263 PTWPAHHPLWGAVPLATPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTN 327
                                                   ..:.:.....::....|.|
Zfish   175 ---------------------------------------DDEDDCDKKDDTGEKKTKH------- 193

  Fly   328 SGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQP---KFRRNRT 389
                           |:..:..|.|..|..|         |:|.|      .|.|   |.||:||
Zfish   194 ---------------SIDGILGDKGRMDEVS---------DVESE------PDLPLKRKQRRSRT 228

  Fly   390 TFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDS- 453
            ||:.|||:||||.|:::|||.:.|||:||.||.|:|||||||||||||:||:....|.:...:.
Zfish   229 TFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHL 293

  Fly   454 -----PSTSSSPTPLVNPVVSPVSPIP-VPVPVAVPESGQQKQPYPYSTSNMCNTSSSSSN---- 508
                 |.|.....|...   .|.|..| ..:|..|..:..:.||.|.||.:....||.||:
Zfish   294 LPGGFPPTGMPTLPTYQ---LPESSYPTTTLPQDVSGTVHRPQPLPPSTMHQGGLSSDSSSAYGL 355

  Fly   509 -----------------SQPCNTINPGSK-MSSKTSSVSSN------QHMEEPAAAVATASPTAS 549
                             |...|.:||.|. :|.:..|:.||      |...|.:.:...:|..||
Zfish   356 SSNRHSFSSYTDTFMSQSASSNHMNPVSNGLSPQVMSILSNPSAVAPQPQHEFSISPLHSSLEAS 420

  Fly   550 APLSMGGENSAFRALPM----TLPMPMTL--PTASAAAFAL-------------SFARQYIAKYM 595
            .|:|   .:.:.|:.|:    :||...:.  ||.|..::::             ..|..|:||.:
Zfish   421 NPIS---ASCSQRSEPIKTADSLPSSQSYCPPTYSTTSYSVDPVTAGYQYSQYGQTAVDYLAKNV 482

  Fly   596 GTP----LNLGHGSSP---IQAQSGR 614
            ...    :.||..|:.   :|.::|:
Zfish   483 SLSTQRRMKLGEHSAVLGLLQVETGQ 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	49/111 (44%)
		Homeobox	388..440	CDD:278475	36/51 (71%)
pax7b	NP_001139621.1	PAX	34..170	CDD:238076	58/150 (39%)
		Homeobox	226..279	CDD:278475	36/52 (69%)
		Pax7	346..389	CDD:289156	10/42 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810