DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and barhl1a

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001017712.2	Gene:	barhl1a / 550407	ZFINID:	ZDB-GENE-050417-212	Length:	299	Species:	Danio rerio

Alignment Length:	242	Identity:	60/242 - (24%)
Similarity:	93/242 - (38%)	Gaps:	53/242 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 ATPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNSSNSN-----------------TTHSNGHN 325
            ::||....:....|:|.........|...:|..|.:..|:                 ...|.|.:
Zfish    46 SSPPSPRRSSVEDAVQRRARALGLDSPLQISQQPRTVTSSFLIRDILADCKPLAACAPYSSTGQS 110

  Fly   326 TNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQPKF---RRN 387
            ......|.|.           |..:|.|........:|:|      |.|.|:||...:.   |:.
Zfish   111 AQDAEDCMDK-----------LHSNSSSDSEYRVKDEADR------EISSSRDSPNSRLKKPRKA 158

  Fly   388 RTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRD 452
            ||.|:..||.:||:.|::..|..|..|.:|||...|::.:|:.|:.|||.||:|...|.|....:
Zfish   159 RTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAE 223

  Fly   453 SPSTSS----SPTPLVNP--VVSPVSPIP----------VPVPVAVP 483
            :.:.|:    .|:|...|  :||.:.|.|          .|.||..|
Zfish   224 AGNYSALQRMFPSPYFYPQSLVSNLDPGPGLYLYRGPSAPPPPVQRP 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	21/51 (41%)
barhl1a	NP_001017712.2	TPP_enzymes	<122..177	CDD:294952	18/60 (30%)
barhl1a	NP_001017712.2	Homeobox	159..211	CDD:278475	21/51 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910