DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and AgaP_AGAP006537

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_001237835.2	Gene:	AgaP_AGAP006537 / 4576611	VectorBaseID:	AGAP006537	Length:	271	Species:	Anopheles gambiae

Alignment Length:	187	Identity:	49/187 - (26%)
Similarity:	70/187 - (37%)	Gaps:	55/187 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 DSGSRDSRSP-DADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNT 413
            |.|:..|... |||.|      |::         |.:|.||||:.||:..|:..|.....|....
Mosquito   128 DDGTTSSEDGLDADGN------GKN---------KTKRIRTTFTEEQIQILQANFQVDSNPDGQD 177

  Fly   414 REKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPV 478
            .|::|..|.||:...||||.|.||:.::|                                 |.|
Mosquito   178 LERIALATGLSKRVTQVWFQNSRARQKKH---------------------------------VHV 209

  Fly   479 PVAVPESGQQKQPYPYSTSNMCNTSSSSSNSQP----CNTINPGSKMSSKTSSVSSN 531
            |.|.......:.....:.:|.|  |||:||..|    ...:.|...:..|||..:|:
Mosquito   210 PRAQDLFNGMRSDLNNNNNNSC--SSSNSNDGPPGHHLGGVGPEDCVLGKTSIFNSH 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	21/51 (41%)
AgaP_AGAP006537	XP_001237835.2	LIM1_AWH	8..61	CDD:188759
		LIM2_AWH	69..123	CDD:188765
		Homeobox	152..204	CDD:278475	21/51 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910