DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and gsx1

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001012251.1	Gene:	gsx1 / 449875	ZFINID:	ZDB-GENE-041008-135	Length:	243	Species:	Danio rerio

Alignment Length:	214	Identity:	59/214 - (27%)
Similarity:	84/214 - (39%)	Gaps:	66/214 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 YGYAIHPTHP-HPYTSFPTWPAH------------------HPLWGAVPLATPPGGGPAGAGGAL 292
            :.||:||:|| |   |......|                  ||...|:||..
Zfish    27 FPYAVHPSHPLH---SLSAGSCHSRKAGLLCFCPLCVTSQLHPSPPALPLIK------------- 75

  Fly   293 QPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSR 357
                  :|:.:.|....:...|..::| |:|.|.|||||...:       :.|.
Zfish    76 ------ASFPAFGTQYCHSALSRQHST-SSGVNLNSGSGLYQA-------AYPV----------- 115

  Fly   358 SPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTA 422
             ||......|.||...|:.|.|     :|.||.|:..||.|||:||..:.|.....|.::|....
Zfish   116 -PDPRQFHCISIENSSSQLQSS-----KRMRTAFTSTQLLELEREFTSNMYLSRLRRIEIATYLN 174

  Fly   423 LSEARVQVWFSNRRAKWRR 441
            |||.:|::||.|||.|.::
Zfish   175 LSEKQVKIWFQNRRVKHKK 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	23/51 (45%)
gsx1	NP_001012251.1	Homeobox	140..192	CDD:278475	23/51 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910