Protein Alignment toe and Ptx1

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Alignment Length: 696
• Identity: 159/696 - (22%)
• Similarity: 234/696 - (33%)
• Gaps: 251/696 - (36%)

  Fly   101 AAALGGIFCGGSAAAGPGAAAAAATNL--------------NALASQHRLLELSRFGLRGYDLAQ 151
            ::|:||  |||....|.|...::||.|              .||.           ||.......
  Fly     4 SSAVGG--CGGGGGLGVGVVTSSATALGPGGLTNGGGGVVSGALN-----------GLEAMSAES 55

  Fly   152 HMLSQQGAVSKLLGTLRPPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLITEGVCTN 216
            ..|..|..||  .||....|..|.::....|.|.:|   .....:.|:..         .|..|:
  Fly    56 TGLCLQDLVS--AGTANGAGSAGSAESATTTSTALS---SGSTGSSTVNG---------GGSSTS 106

  Fly   217 AT------------------APSVSSINRI-----LRNRAAERAAAEFARAASYGYAIHPTH--- 255
            .|                  :|::||:..|     |.:.|.:....        ||:.||.|
  Fly   107 GTEHLHSHHSLHDSSSSVSISPAISSLMPISSLSHLHHSAGQDLVG--------GYSQHPHHTVV 163

  Fly   256 -PHPYTSFPTWPAHHPL-----WGAVPLATPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNSS 314
             ||.       |.|.||     |..                      :|....|..:|::..||.
  Fly   164 PPHT-------PKHEPLEKLRIWAE----------------------TGDFRDSHSSMTAVANSL 199

  Fly   315 NSNTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMID---IEGEDSES 376
            :|  ||.|...|:|.|                 |..:.|||.:    |.||.::   |:.|:..|
  Fly   200 DS--THLNNFQTSSTS-----------------SISNRSRDRK----DGNRSVNETTIKTENISS 241

  Fly   377 QDSDQP---------------KFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEA 426
            ...|:|               :.||.||.|:.:||.|||..|.::.||.::|||::|..|.|:||
  Fly   242 SGHDEPMTTSGEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEA 306

  Fly   427 RVQVWFSNRRAKWRRHQRVNLIKQ-------------------RDSPSTSSSPTPLVNPVVSPVS 472
            ||:|||.|||||||:.:| |.:..                   .|....||.|......|.||:.
  Fly   307 RVRVWFKNRRAKWRKRER-NAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLG 370

  Fly   473 PIPVPVPV-----AVPESGQQKQPYPYST--------------------SNMCNTSSSSSNSQPC 512
            ..|.|.||     .|..:..|.....::|                    |::.|||:..:...||
  Fly   371 TKPFPWPVNPLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPC 435

  Fly   513 NTINPGS-----------KMSSKTSSVSSNQHMEEPAAAVATASPTASAPLSMGGENSAFRALPM 566
            ....|.:           ..||.:||:::.:...:..|:....|| .|||..:...|||..:...
  Fly   436 PYTTPANPYMYRSAAEPCMSSSMSSSIATLRLKAKQHASAGFGSP-YSAPSPVSRSNSAGLSACQ 499

  Fly   567 TLPMPMTLPTASAAAFALSFARQYIAKYM--------GTP---------------LNLGH----- 603
            ...:.:|... ..|..||....|:..::.        |.|               |.|.|
  Fly   500 YTGVGVTDVVXENALGALLNQHQHHLQHFSGGSVGGSGVPNGMQQHSGNMLHHSNLGLDHSDLGL 564

  Fly   604 -GSSPIQAQSGRDHQSE--------------EREYEDEQEEEEVIN 634
             |..|...|...:|..|              .....::.::|:||:
  Fly   565 VGGGPSNHQDEGNHSLEGSNKSPMEAPLANSSNNNNNDNDDEDVID 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	21/118 (18%)
		Homeobox	388..440	CDD:278475	29/51 (57%)
Ptx1	NP_001138130.2	Homeobox	268..320	CDD:278475	29/51 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450805
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840