DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and mix1

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_988848.1	Gene:	mix1 / 394439	XenbaseID:	XB-GENE-485898	Length:	357	Species:	Xenopus tropicalis

Alignment Length:	285	Identity:	74/285 - (25%)
Similarity:	110/285 - (38%)	Gaps:	93/285 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   352 GSR--DSRSPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTR 414
            ||:  |.|:|..||:.:       ..||       ||.||.|:..|||.||:.|..:.||.::.|
Frog    67 GSKETDPRNPVPDASLL-------PASQ-------RRKRTFFTQAQLDILEQFFQTNMYPDIHHR 117

  Fly   415 EKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVP 479
            |:||....:.|:|:||||.|||||.||         :.:.:|        .||::
Frog   118 EELARHIYIPESRIQVWFQNRRAKVRR---------QGAKAT--------KPVLA---------- 155

  Fly   480 VAVPESGQQKQPYPYSTSNMCNTSSSSSNSQPCNTINPGSKMSSKTSSVSSNQHMEEPAAAVATA 544
                       .:.||::.                   |:..|...|:.:.|......|.|.|.|
Frog   156 -----------GHHYSSTF-------------------GATRSMFPSAPAPNSSSHPMATARAQA 190

  Fly   545 SPTASAPLSMGGENSAFRALPMTLPMPMTLPTASAAAFALSFARQYIAKYMGTP--LNLGHGSSP 607
            .|...:..:...::..|      ||.|.:....|...|.||.|         ||  .:|...||.
Frog   191 QPMKDSQANKFHQSQGF------LPYPDSSCDVSRQRFLLSQA---------TPGTYHLPQTSSN 240

  Fly   608 IQAQSGRDH---QSEEREYEDEQEE 629
            |..|:|:.|   .:::..|.|..|:
Frog   241 IYNQNGKPHIPLWNQQPLYTDMMEK 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	26/51 (51%)
mix1	NP_988848.1	Homeobox	90..143	CDD:278475	26/52 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000