Protein Alignment toe and UNCX

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001073930.1
• Gene: UNCX / 340260
• HGNCID: 33194
• Length: 531
• Species: Homo sapiens
• Alignment Length: 477
• Identity: 105/477 - (22%)
• Similarity: 144/477 - (30%)
• Gaps: 208/477 - (43%)

  Fly   228 ILRNRAAERAAAEFARAAS--YGYAIHPTHPHPYTSFPTWPAHHPLWGAVPLATPP-------GG 283
            ::..|..|...|:|..:..  .|:.....|.|.|..     |.|.|..|...|:.|       ||
Human     1 MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYEL-----AGHQLQSAAAAASVPFSIDGLLGG 60

  Fly   284 GPAGAGGALQP----------GGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAG 338
            ..|.|...:.|          ||.|..:
Human    61 SCAAAASVVNPTPLLPAACGVGGDGQPF------------------------------------- 88

  Fly   339 SGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEF 403
              :||      |||..|..||..                     |.||.||.|:..||:||||.|
Human    89 --KLS------DSGDPDKESPGC---------------------KRRRTRTNFTGWQLEELEKAF 124

  Fly   404 DKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSSSPTPLVNPVV 468
            ::||||.|..||.||.|..|.|:||||||.|||||||:.:  |..|....|:.:|.||......:
Human   125 NESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKE--NTKKGPGRPAHNSHPTTCSGEPM 187

  Fly   469 SP----------------------------------------------------VSPIP------ 475
            .|                                                    :||.|
Human   188 DPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPP 252

  Fly   476 ---------------VPVPVAVPESGQQKQP--YPYSTSNMCNTSSSSSNSQP---------CNT 514
                           .|.|...|.:.....|  ||        :..|.:..||         ..:
Human   253 AAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYP--------SQRSGAGPQPRPGRPADKDAAS 309

  Fly   515 INPGSKMSS--------------KTSSVSSNQHMEEPAAAVATASPTAS---------APLSMGG 556
            ..||:.:::              ...|:.|:......||:.|.|:..|.         ||.::.|
Human   310 CGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIG 374

  Fly   557 ENSAFRALPMTLPMPMTLPTAS 578
            :.. |...|:|.|:...:|.|:
Human   375 KGH-FLLYPITQPLGFLVPQAA 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	0/1 (0%)
		Homeobox	388..440	CDD:278475	33/51 (65%)
UNCX	NP_001073930.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	87..107		9/85 (11%)
		Homeobox	108..161	CDD:306543	33/52 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..312		20/160 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..344		2/19 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..531

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910