DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and prrx1b

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_017207930.1	Gene:	prrx1b / 337089	ZFINID:	ZDB-GENE-030131-9033	Length:	267	Species:	Danio rerio

Alignment Length:	247	Identity:	78/247 - (31%)
Similarity:	112/247 - (45%)	Gaps:	33/247 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   306 NMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIE 370
            |:.:..|.|.|:...........||...:|...:||..|.:....|||..::.           |
Zfish    29 NLQAKKNFSVSHLLDLEEAREMVGSQVDESVGETGRTMLESPGLTSGSDTTQQ-----------E 82

  Fly   371 GEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNR 435
            .|...|::..:.|.|||||||:..||..||:.|:::|||....||.||.|..|:||||||||.||
Zfish    83 NEQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNR 147

  Fly   436 RAKWRRHQRVNLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVP--------------VAVPESG 486
            |||:||::|..|..:..|...|.|..  |..|..|:.|.|.|.|              ...||.|
Zfish   148 RAKFRRNERAMLASKNASLLKSYSGD--VTAVEQPIVPRPAPRPNDYLSWGSAAPYSWYPRPEGG 210

  Fly   487 QQKQP---YPYSTSNMCN---TSSSSSNSQPCNTINPGSKMSSKTSSVSSNQ 532
            ..:.|   .|..::.|..   |.::::::|..|..|..:.:..|....:.||
Zfish   211 PMRVPQKMLPTESNTMATYPPTCANTTSTQGMNMANSIANLRLKAKEYNLNQ 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	31/51 (61%)
prrx1b	XP_017207930.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910