DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment toe and HOXA7

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_008827.2	Gene:	HOXA7 / 3204	HGNCID:	5108	Length:	230	Species:	Homo sapiens

Alignment Length:	201	Identity:	51/201 - (25%)
Similarity:	80/201 - (39%)	Gaps:	51/201 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 SSYGSDGNMSSN---------PNSSNSN---------TTHSNGHNTNS-------GSGCGDSSAG 338
            |.|.:..::..|         |||..|.         :|....:|.||       .||.|..:..
Human    12 SKYTAGASLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSPLYQSPFASGYGLGADA 76

  Fly   339 SGRL-------SLPALSPD--SGSRDSRSPD-----ADANRMIDIEGEDSESQDSDQPKFRRNRT 389
            .|.|       ::|.|..|  .|:.|.....     |:||..|      .....|..|..:|.|.
Human    77 YGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRI------YPWMRSSGPDRKRGRQ 135

  Fly   390 TFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSP 454
            |::..|..||||||..:.|.....|.::|....|:|.::::||.|||.||::..:      .:.|
Human   136 TYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK------DEGP 194

  Fly   455 STSSSP 460
            :.:::|
Human   195 TAAAAP 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	20/51 (39%)
HOXA7	NP_008827.2	Antp-type hexapeptide	119..124		1/10 (10%)
		Homeobox	134..186	CDD:278475	20/51 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..230		2/20 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910