Protein Alignment toe and Vsx2

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 647
• Identity: 138/647 - (21%)
• Similarity: 204/647 - (31%)
• Gaps: 234/647 - (36%)

  Fly    36 QSPGAIMPMAAVPLPSHLQLLGSSAGGVGQPAAITPVSPTAATTVLAQPHSLSPSTPILTQGAPP 100
            :||.||.           :|||.:.....:  |.|.::.||..||..:..  :|:.|..|.....
  Fly     4 RSPFAIQ-----------ELLGLAVAAATE--APTDLTTTAGATVAKERQ--TPTPPKTTNATMA 53

  Fly   101 AAALGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYDLAQHMLSQQGAVSKLLG 165
            .||.              :||.|||..||..
  Fly    54 TAAT--------------SAATAATPTNAAE---------------------------------- 70

  Fly   166 TLRPPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLITEGVCTNATAPSVSSINRILR 230
                     |:...|:.|....:.:|.::::......:.||    ....|.|.|..::..|
  Fly    71 ---------GNLTSVSEPQQQPQQQQQEQQHHQPHHHQYRE----HHQMTMAAASRMAYFN---- 118

  Fly   231 NRAAERAAAEFARAASYGYAIHPTHPHPYTSFPTWPAHHPLWGAV--PLATPPGGGPAGAGGALQ 293
               |..|.|..........|:|..|.|.:...|....||| .|||  |...||
  Fly   119 ---AHAAVAAAFMPHQLAAAVHHHHQHQHQHHPHHHPHHP-HGAVGGPPPPPP------------ 167

  Fly   294 PGGSGSSYGSDGNMSSNPNSSNSNTTHSNG--HNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDS 356
                        ....:|:..:....|:.|  ...:..:|.|....||       |:|.....:|
  Fly   168 ------------MQHHHPHHPHHPLLHAQGFPQLKSFAAGAGTCLPGS-------LAPKDFGMES 213

  Fly   357 RSPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAART 421
            .:...        .|.:|:.:   :.|.|.:||.|:..||::||:.|.::|||.|..||.|:.:|
  Fly   214 LNGFG--------VGPNSKKK---KKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKT 267

  Fly   422 ALSEARVQVWFSNRRAKWRRHQRV-------------------------NLIKQ----------- 450
            .|.|.|:||||.|||||||:.::|                         .::|.
  Fly   268 ELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHSLPLPDTILKSAKDNDAVAPWL 332

  Fly   451 -------------------RDSPSTS------------------------SSPTPLVNPVVSPVS 472
                               :|....|                        ||.|..:| |||
  Fly   333 LGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSRSRCHALSSSTESLN-VVS--- 393

  Fly   473 PIPVPVPVAVPESGQQKQPYPYSTSNMCN---------TSSSSSNSQPCNTINPGSKMSSKTSSV 528
                |.|.:.|.|.....| |.|||....         |.:|::||.....|..||....:...:
  Fly   394 ----PAPSSCPTSASTSAP-PTSTSGYAGAASSAATTPTGASTTNSSSSPHIELGSPSPQQQQHL 453

  Fly   529 SSNQHMEEPA-------AAVATASPTASAPLSMGGENSAFRALPMTLPMPMTLPTASAAAFA 583
            ...|..::.|       |.|...:|.:..||......:...|...:....|.:.||.|||.|
  Fly   454 QLQQQQQQQASLYLGAGAVVTGCAPPSYHPLLDAANAAGAGAAASSKDFHMIMNTAVAAAAA 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	10/95 (11%)
		Homeobox	388..440	CDD:278475	28/51 (55%)
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	28/52 (54%)
		OAR	556..570	CDD:281777

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450810
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840