Protein Alignment toe and pax3a

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_571352.1
• Gene: pax3a / 30532
• ZFINID: ZDB-GENE-980526-52
• Length: 509
• Species: Danio rerio
• Alignment Length: 574
• Identity: 165/574 - (28%)
• Similarity: 236/574 - (41%)
• Gaps: 156/574 - (27%)

  Fly    60 AGGVGQPAAITPVSPTAATTVLAQPHSLSPSTPILTQGAPPAAALGGIFCGGSAAAGPGAAAAAA 124
            |||:.:     .:.||.........:||..|||:   |......|||:|..|....
Zfish     5 AGGISR-----MMRPTPPQNYPRGGYSLEVSTPL---GQGRVNQLGGVFINGRPLP--------- 52

  Fly   125 TNLNALASQHRLLELSRFGLRGYDLAQHMLSQQGAVSKLL------GTLRPPGLIGGSKPKVA-T 182
               |.:  :|:::|::..|:|...:::.:....|.|||:|      |::| ||.|||||||.: |
Zfish    53 ---NHI--RHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR-PGAIGGSKPKQSTT 111

  Fly   183 PTVVSKIEQYKRENPTIFAWEIRERLITEGVCTNATAPSVSSINRILRNRAAERAAAEFARAASY 247
            |.|..|||:||||||.:|:||||::|:.:|:|.....||||||:|:||        .:|
Zfish   112 PDVEKKIEEYKRENPGMFSWEIRDKLLKDGICDRNNVPSVSSISRMLR--------CKF------ 162

  Fly   248 GYAIHPTHPHPYTSFPTWPAHHPLWGAVPLATPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPN 312
                                                           ||:|.....|..:.....
Zfish   163 -----------------------------------------------GGNGDEDEDDDEVEKREI 180

  Fly   313 SSNSNTTHSNGHNTNSGSG-CGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSES 376
            ..|....      .:|..| .||.|:.|          |.||.....|.....|
Zfish   181 EENERRA------KHSIDGILGDRSSHS----------DEGSDVDSEPGLPLKR----------- 218

  Fly   377 QDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRR 441
                  |.||:||||:.|||:|||:.|:::|||.:.|||:||.|..|:|||||||||||||:||:
Zfish   219 ------KQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 277

  Fly   442 HQRVN-------LIKQRDSPSTSSS--PTPLVNPVVSPVSPIPVPVPVAVPESGQQKQPYPYSTS 497
            ....|       ||.....||..||  |..|.:   ||..|..:......|.:..:.||.|.::.
Zfish   278 QAGANQLMAFNHLIPGGFPPSAMSSLQPYQLAD---SPYPPSSISQVSEQPSTVHRPQPLPPTSV 339

  Fly   498 NMCNTSSSSSNSQPCNTINPGSKMSSKTSSVSSNQHMEEPAAAVATASPTASAPLSMGGENSAFR 562
            :.....|           .||::..|....:||.:|.....:....|:|..:.|::....|
Zfish   340 HQSGLGS-----------GPGAQEGSSAYCLSSGRHGFSGYSDGYVAAPGHANPVNPSISN---- 389

  Fly   563 ALP---MTLPMPMTLPTASAAAFALSFARQYIAKYMGTPLNLGHGSSPIQAQSG 613
            .||   |.|..|..:|....:.||||.....:....|.|.:. |.|..::|..|
Zfish   390 GLPSQVMGLLNPGAVPHQPQSDFALSPLTGGLEPSTGMPASC-HSSQRLEALPG 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	47/102 (46%)
		Homeobox	388..440	CDD:278475	34/51 (67%)
pax3a	NP_571352.1	PAX	34..159	CDD:128645	54/139 (39%)
		Homeobox	223..276	CDD:278475	34/52 (65%)
		Pax7	350..394	CDD:289156	10/47 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810