DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment toe and msx1a

DIOPT Version :9

Sequence 1:NP_524041.2 Gene:toe / 39418 FlyBaseID:FBgn0036285 Length:640 Species:Drosophila melanogaster
Sequence 2:NP_571348.1 Gene:msx1a / 30527 ZFINID:ZDB-GENE-980526-312 Length:233 Species:Danio rerio


Alignment Length:184 Identity:48/184 - (26%)
Similarity:78/184 - (42%) Gaps:39/184 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   343 SLPALSPDSGSRDSR-SPDADANRMIDIE------GEDSESQDSDQPKF---------------- 384
            |:.||..|  .|.:| ||||||.....:|      ..:|..:.:..|:.                
Zfish    45 SVEALMAD--RRPNRGSPDADARLGFSVEVLQLPVKAESPERSTWVPRARFSPSRLSPPACPLRK 107

  Fly   385 ----RRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRV 445
                |:.||.||..||..||::|.:..|..:..|.:.::..:|:|.:|::||.|||||.:|.|..
Zfish   108 HKTNRKPRTPFSTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEA 172

  Fly   446 NLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVPVAVPESGQQKQPYPYSTSNM 499
            .|.|.:.:          ..|::.|...|..|....:|.......|:...::|:
Zfish   173 ELEKLKMA----------AKPLLPPAFGISFPAGAHIPAYSAGSHPFHRHSANV 216

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
toeNP_524041.2 HTH 134..230 CDD:304362
Homeobox 388..440 CDD:278475 21/51 (41%)
msx1aNP_571348.1 Homeobox 114..167 CDD:278475 21/52 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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