DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and hoxb8b

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_571256.1	Gene:	hoxb8b / 30420	ZFINID:	ZDB-GENE-980526-291	Length:	247	Species:	Danio rerio

Alignment Length:	191	Identity:	53/191 - (27%)
Similarity:	80/191 - (41%)	Gaps:	40/191 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 PLATPP-GGGPA-----GAGGALQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGD 334
            |..||. ||.|:     ..|.|.|.......:...|. ||.|::|...|..:..:.       ||
Zfish    27 PSYTPDLGGRPSVLYGHNTGSAFQHAAQFPDFYHHGT-SSFPHASYQQTPCAVAYP-------GD 83

  Fly   335 SSAGSGRLSLPALSPDSGSRDS--RSPDADANRMID----IEG--EDSESQDSDQPKF------- 384
            ::..       .|..|...:.|  .:||:|..:..|    :.|  :|.||.:....:.
Zfish    84 ATGN-------ILGQDGLQKQSFFGAPDSDFTQFGDCNLKVSGIRDDLESAEPCTAQLFPWMRPQ 141

  Fly   385 ----RRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRR 441
                ||.|.|:|..|..||||||..:.|.....|.:::...||:|.:|::||.|||.||::
Zfish   142 ATGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKK 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	22/51 (43%)
hoxb8b	NP_571256.1	Antp-type hexapeptide	134..139		0/4 (0%)
		Homeobox	149..201	CDD:278475	22/51 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..247		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910