DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and Rhox9

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001020045.1	Gene:	Rhox9 / 298352	RGDID:	1563844	Length:	227	Species:	Rattus norvegicus

Alignment Length:	254	Identity:	58/254 - (22%)
Similarity:	84/254 - (33%)	Gaps:	66/254 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   241 FARAASYGYAIHPTHPHPYTSFPTWPAHHPLWGAVPLATPPGGGPAGAGGALQPGGSGSSYGSDG 305
            |.::.|.|..:.|...|..|:            .|..|...|.......|.|..||......:.|
  Rat    11 FQKSLSLGAEVDPEQQHGGTA------------VVSEAREVGDQSQRLVGGLVQGGLDQGQPTQG 63

  Fly   306 NMSSNPNSSNSNTTHSNGHNTNSGSGCGDSS--------AGSGRLSLPALSPDSGSRDSRSPDAD 362
            .::............|...........||..        ||.|     |..|:..:
  Rat    64 QLAGGNLPQEEPAELSLAQEATGVEEEGDEKEEEMEARYAGDG-----AYGPEDNN--------- 114

  Fly   363 ANRMIDIEGEDSESQDSDQPKF--------------------RRNRTTFSPEQLDELEKEFDKSH 407
                :..|| |....|.:||:.                    |..|..|:..||.:||:.|.::.
  Rat   115 ----VQQEG-DQHPNDQEQPQQEAAIPEGNRGQQAGNRLVHPRHTRPRFTHSQLRDLERLFQETR 174

  Fly   408 YPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSSSPTPLVNP 466
            ||.:.||:.||....:.|:.||.||..||:.:||:.|  |:...:.|     |.|..||
  Rat   175 YPSLRTRKDLARWMGVPESDVQDWFRMRRSLFRRNSR--LLMFCELP-----PIPENNP 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	20/51 (39%)
Rhox9	NP_001020045.1	Homeobox	154..207	CDD:278475	20/52 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910