DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment toe and Mixl1

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001099449.1	Gene:	Mixl1 / 289311	RGDID:	1310011	Length:	231	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	80/301 - (26%)
Similarity:	110/301 - (36%)	Gaps:	94/301 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 AAERAAAEFARAASYGYAIHPTHPHPYTSFPTWPAHHPLWGAVPLATPPGGGPAGAGGALQPGGS 297
            ||.....:||..|               :|||:||.||....:|.|.|..|.|...
  Rat     3 AAGSQQLQFAEGA---------------AFPTFPAAHPGGQLLPAARPATGLPPAP--------- 43

  Fly   298 GSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDAD 362
                                               .||.|       ||.:|...||..| |.|.
  Rat    44 -----------------------------------PDSRA-------PAATPCFPSRGPR-PAAQ 65

  Fly   363 ANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEAR 427
            ....:|..|....|.....|: ||.||:||.|||..||..|.::.||.::.||:|||.|.|.|:|
  Rat    66 TPTGLDPPGPSKGSAAPSAPQ-RRKRTSFSSEQLQLLELVFRQTMYPDIHLRERLAALTLLPESR 129

  Fly   428 VQVWFSNRRAKWRRH----------QRVNLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVPVAV 482
            :||||.|||||.||.          :|.:.: .|.:|.|.:.       .:.|..|:...|...:
  Rat   130 IQVWFQNRRAKSRRQSGKSFQPLSSRREDFL-HRPAPGTEAR-------CLKPQLPLEADVNHVL 186

  Fly   483 PESGQQKQPYPYSTSNMCNTSSSSSNSQPCNTINPGSKMSS 523
            ..|        .:...:|.:.|....:....:.:.|||:.|
  Rat   187 DSS--------MAGGGVCTSGSQGFETYSSLSEDIGSKLDS 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	30/51 (59%)
Mixl1	NP_001099449.1	PRK14971	<2..139	CDD:237874	61/203 (30%)
Mixl1	NP_001099449.1	Homeobox	89..143	CDD:395001	30/53 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810