DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and sebox

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001306981.1	Gene:	sebox / 282666	ZFINID:	ZDB-GENE-021206-4	Length:	293	Species:	Danio rerio

Alignment Length:	266	Identity:	70/266 - (26%)
Similarity:	109/266 - (40%)	Gaps:	60/266 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 SPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTA 422
            ||:.|  |...:||:.           :|.||.||..||.|||:.|..:.||.:..||:|||.|.
Zfish    45 SPELD--RTGHVEGQR-----------KRKRTIFSRAQLSELERAFMITPYPDITLRERLAALTL 96

  Fly   423 LSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPS---TSSSPTPLVNPVVSP-------------- 470
            |.|:::||||.||||:..:.:::.....|.||:   |..:..|.:|...||
Zfish    97 LPESKIQVWFQNRRARSMKSKKLITPVSRRSPAKDCTFPATHPDLNLEQSPEANKSLRHHQQSLI 161

  Fly   471 ---VSPIP---VPVPVAVPESGQQKQPYPYSTSNMCNTSSSSSNSQPCNTI-NPGSKMSSKTSSV 528
               ::|.|   .|:...:||..|      ::..|......||.:|.|...| :|....||....:
Zfish   162 RQALNPWPQNRPPISPDLPEILQ------WANRNSETPGDSSFSSCPSERIQHPFPNQSSSVWQM 220

  Fly   529 SSNQHMEEPAAAVATASPTASAPLSMGGENSAFRALPMTLPMPMTLPTASAAAFALSFARQYIAK 593
            :......|...:..|.|                :||..::.:...:| |..::...:..||.:..
Zfish   221 NCFAAHPEGLKSYCTTS----------------QALYSSVSVDQMIP-AHPSSLEEALQRQALTH 268

  Fly   594 YMGTPL 599
            |..|.|
Zfish   269 YPQTSL 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	28/51 (55%)
sebox	NP_001306981.1	COG5576	13..159	CDD:227863	43/126 (34%)
		Homeobox	61..112	CDD:278475	27/50 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	117..144		6/26 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810