Protein Alignment toe and Pax6

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_006234695.1
• Gene: Pax6 / 25509
• RGDID: 3258
• Length: 436
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 158/509 - (31%)
• Similarity: 221/509 - (43%)
• Gaps: 152/509 - (29%)

  Fly   104 LGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYDLAQHMLS------------- 155
            |||:|..|.....              :::.:::||:..|.|..|:::.:.:
  Rat    11 LGGVFVNGRPLPD--------------STRQKIVELAHSGARPCDISRILQTHADAKVQVLDSEN 61

  Fly   156 -QQGAVSKLL------GTLRPPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLITEGV 213
             ..|.|||:|      |::||.. ||||||:||||.|||||.|||||.|:|||||||:||::|||
  Rat    62 VSNGCVSKILGRYYETGSIRPRA-IGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGV 125

  Fly   214 CTNATAPSVSSINRILRNRAAERAAAEFARAASYGYAIHPTHPHPYTSFPTWPAHHPLWGAVPLA 278
            |||...||||||||:|||.|:|:     .:..:.|.         |............||
  Rat   126 CTNDNIPSVSSINRVLRNLASEK-----QQMGADGM---------YDKLRMLNGQTGSWG----- 171

  Fly   279 TPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCG-DSSAGSGRL 342
            |.||..|    |...||              .|...........|.||||.|..| ||.....||
  Rat   172 TRPGWYP----GTSVPG--------------QPTQDGCQQQEGQGENTNSISSNGEDSDEAQMRL 218

  Fly   343 SLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSH 407
            .|                                    :.|.:||||:|:.||::.|||||:::|
  Rat   219 QL------------------------------------KRKLQRNRTSFTQEQIEALEKEFERTH 247

  Fly   408 YPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDS------PSTSSSPTPLVNP 466
            ||.|..||:|||:..|.|||:|||||||||||||.:::...:::.|      |.:||..|.:..|
  Rat   248 YPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQP 312

  Fly   467 VVSPVSPI------------------------PVPVPVAVPESGQQKQPYPYSTSN-MCNTSSSS 506
            :..|.:|:                        |:| ...:..:...:.|.|..||: .|...:|.
  Rat   313 IPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMP-SFTMANNLPMQPPVPSQTSSYSCMLPTSP 376

  Fly   507 S-NSQPCNTINP---GSKMSSKTSSVSSNQHMEEPAAAVATASPTASAPLSMGG 556
            | |.:..:|..|   .:.|:|:....|.       ..:....||..|.|:.:.|
  Rat   377 SVNGRSYDTYTPPHMQTHMNSQPMGTSG-------TTSTGLISPGVSVPVQVPG 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	57/115 (50%)
		Homeobox	388..440	CDD:278475	33/51 (65%)
Pax6	XP_006234695.1	PAX	4..142	CDD:128645	62/145 (43%)
		Homeobox	228..281	CDD:395001	34/52 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910