DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and Msx2

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_037114.2	Gene:	Msx2 / 25483	RGDID:	3116	Length:	267	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	68/243 - (27%)
Similarity:	100/243 - (41%)	Gaps:	59/243 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 PGGGPAGA-GGALQPGGSGSS--YGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRL 342
            ||.||.|| |||.:.....||  :..:..||.......|.....:         |    |.:|.:
  Rat    24 PGPGPGGAEGGAEERRVKVSSLPFSVEALMSDKKPPKESPAVPPD---------C----ASAGAV 75

  Fly   343 SLPALSPDSGSRDSRSPD--ADANRMIDIEGEDSE---------SQDSDQPKF------------ 384
            ..|.|.|..|.||:.||.  ........::.|:||         .:.|..|:.
  Rat    76 LRPLLLPGHGVRDAHSPGPLVKPFETASVKSENSEDGAPWIQEPGRYSPPPRHMSPTTCTLRKHK 140

  Fly   385 --RRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNL 447
              |:.||.|:..||..||::|.:..|..:..|.:.::...|:|.:|::||.|||||.:|.|...|
  Rat   141 TNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAEL 205

  Fly   448 IKQRDS-----PSTSSSPTPLVNPVVS------------PVSPIPVPV 478
            .|.:.:     ||..|.|.|:.:|:.:            ||.||| ||
  Rat   206 EKLKMAAKPMLPSGFSLPFPINSPLQAASIYSASYPFHRPVLPIP-PV 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	20/51 (39%)
Msx2	NP_037114.2	Homeobox	145..199	CDD:395001	20/53 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910