Protein Alignment toe and Pax9

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_035171.1
• Gene: Pax9 / 18511
• MGIID: 97493
• Length: 342
• Species: Mus musculus
• Alignment Length: 265
• Identity: 88/265 - (33%)
• Similarity: 121/265 - (45%)
• Gaps: 55/265 - (20%)

  Fly   104 LGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYDLAQHMLSQQGAVSKLLGTLR 168
            |||:|..|....            ||:  :.|::||::.|:|..|:::.:....|.|||:|....
Mouse    11 LGGVFVNGRPLP------------NAI--RLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYN 61

  Fly   169 P-----PGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLITEGVCTNATAPSVSSINRI 228
            .     ||.||||||:|.|||||..|..||:.:|.|||||||:||:.:|||.....||||||:||
Mouse    62 ETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRI 126

  Fly   229 LRNRAAERAAAEFARAASY-GYAIHPTHPH---PYTSFPTWPAHHPLWGAVPLATPPGGGPAGAG 289
            |||:     ....|:...| .|..|...|.   ||....::|:  |:..|......|.|.||..|
Mouse   127 LRNK-----IGNLAQQGHYDSYKQHQPAPQPALPYNHIYSYPS--PITAAAAKVPTPPGVPAIPG 184

  Fly   290 GALQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDSS----------AGSGRLSL 344
            ....|....||:               :.|...|..:.:..|..|||          :..||.:.
Mouse   185 SVALPRTWPSSH---------------SVTDILGIRSITDQGVSDSSPYHSPKVEEWSSLGRNNF 234

  Fly   345 PALSP 349
            ||.:|
Mouse   235 PAAAP 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	49/100 (49%)
		Homeobox	388..440	CDD:278475
Pax9	NP_035171.1	PAX	6..131	CDD:238076	59/138 (43%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	7..63		18/65 (28%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	82..130		29/47 (62%)
		Interaction with KDM5B. /evidence=ECO:0000250	168..189		6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910