Protein Alignment toe and Pax7

DIOPT Version :10

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_006538692.1
• Gene: Pax7 / 18509
• MGIID: 97491
• Length: 505
• Species: Mus musculus
• Alignment Length: 589
• Identity: 166/589 - (28%)
• Similarity: 232/589 - (39%)
• Gaps: 222/589 - (37%)

  Fly    19 SLPGAAPAIPATATAGSQSPGAIMPMAAVPLPSHLQLLGSSAGGVGQPAAITPVSPTAATTVLAQ 83
            :||||.|.:.      ...||...|....|
Mouse     3 ALPGAVPRMM------RPGPGQNYPRTGFP----------------------------------- 26

  Fly    84 PHSLSPSTPILTQGAPPAAALGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYD 148
               |..|||:   |......|||:|..|....            |.:  :|:::|::..|:|...
Mouse    27 ---LEVSTPL---GQGRVNQLGGVFINGRPLP------------NHI--RHKIVEMAHHGIRPCV 71

  Fly   149 LAQHMLSQQGAVSKLL------GTLRPPGLIGGSKPK-VATPTVVSKIEQYKRENPTIFAWEIRE 206
            :::.:....|.|||:|      |::| ||.||||||: ||||.|..|||:||||||.:|:||||:
Mouse    72 ISRQLRVSHGCVSKILCRYQETGSIR-PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRD 135

  Fly   207 RLITEGVCTNATAPS--VSSINRILRNRAAERAAAEFARAASYGYAIHPTHPHPYTSFPTWPAHH 269
            ||:.:|.|..:|.||  ||||:|:||.:..::...|
Mouse   136 RLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEDDE----------------------------- 171

  Fly   270 PLWGAVPLATPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGD 334
                                       .|.....||...:
Mouse   172 ---------------------------EGDKKEEDGEKKA------------------------- 184

  Fly   335 SSAGSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQP---KFRRNRTTFSPEQL 396
                  :.|:..:..|.|:|            :| ||.|.|| :.|.|   |.||:||||:.|||
Mouse   185 ------KHSIDGILGDKGNR------------LD-EGSDVES-EPDLPLKRKQRRSRTTFTAEQL 229

  Fly   397 DELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSSSP- 460
            :||||.|:::|||.:.|||:||.||.|:|||||||||||||:||:....|.:...:.......|
Mouse   230 EELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPP 294

  Fly   461 --TPLVNPVVSPVSPIPVPVPVAVPESG----QQKQPYPYSTSNM---------CNTSSS----- 505
              .|.:.|...|.|..|.   ..:.:.|    .:.||.|.||.:.         .:|||:
Mouse   295 TGMPTLPPYQLPDSTYPT---TTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARH 356

  Fly   506 --SSNSQ-------PCNTINPGSK-MSSKTSSVSSNQHMEEPAAAVATASPTASAPLSM----GG 556
              ||.|.       |.|.:||.|. :|.:..|:.||     |:|    ..|...|..|:    ||
Mouse   357 SFSSYSDSFMNPGAPSNHMNPVSNGLSPQVMSILSN-----PSA----VPPQPQADFSISPLHGG 412

  Fly   557 ENSA 560
            .:||
Mouse   413 LDSA 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH_ARSR	134..230	CDD:481197	50/104 (48%)
		Homeodomain	385..441	CDD:459649	39/55 (71%)
Pax7	XP_006538692.1	PAX	34..161	CDD:128645	57/141 (40%)
		Homeodomain	218..274	CDD:459649	39/55 (71%)
		Pax7	347..385	CDD:403540	12/37 (32%)