Protein Alignment toe and Pax5

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_032808.1
• Gene: Pax5 / 18507
• MGIID: 97489
• Length: 391
• Species: Mus musculus
• Alignment Length: 525
• Identity: 132/525 - (25%)
• Similarity: 193/525 - (36%)
• Gaps: 175/525 - (33%)

  Fly    89 PSTPILTQGAPPAAALGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYDLAQHM 153
            |:...:..|......|||:|..|...  |...            :.|::||:..|:|..|:::.:
Mouse     8 PTPRTIRTGHGGVNQLGGVFVNGRPL--PDVV------------RQRIVELAHQGVRPCDISRQL 58

  Fly   154 LSQQGAVSKLLGTLR-----PPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLITEGV 213
            ....|.|||:||...     .||:|||||||||||.||.||.:|||:|||:||||||:||:.|.|
Mouse    59 RVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERV 123

  Fly   214 CTNATAPSVSSINRILRNRAAERAAAEFARAASYGYAIHPTHPHPYTSFPTWPAHHPLWGAVPLA 278
            |.|.|.|||||||||:|.:..:
Mouse   124 CDNDTVPSVSSINRIIRTKVQQ------------------------------------------- 145

  Fly   279 TPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRLS 343
             ||                           :.|..::|::..|.|..|...|...||:..|..:
Mouse   146 -PP---------------------------NQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSI- 181

  Fly   344 LPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQPK--------FRRNR---TTFSPEQLD 397
                   ||.....||.||.|:    ...|...|:|..|.        |.|.:   ..|:.:||:
Mouse   182 -------SGILGITSPSADTNK----RKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLE 235

  Fly   398 ELEKEFDKSHYPCVNTR------EKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPST 456
            .|::.|::.||..:.|.      |:....:|::..          |......:.||.....:...
Mouse   236 VLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASL----------AGGLDDMKANLTSPTPADIG 290

  Fly   457 SSSPTPLVNPVVS--PVSPIPVP-VPVAVPESGQQKQPYPYSTSNMCNTSSSSSNSQPCNTINPG 518
            ||.|.|...|:|:  .::...:| .|..||.:||.....|..|..:                 ||
Mouse   291 SSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMV-----------------PG 338

  Fly   519 SKMSS------KTSSVSSNQHMEEPAAAVATASPTASAPLSMGGENSAFRALPMTLPMPMTLPTA 577
            |:.|.      :.||.:.:.....|.   ...||...:|.:.|                 ..|.|
Mouse   339 SEFSGSPYSHPQYSSYNDSWRFPNPG---LLGSPYYYSPAARG-----------------AAPPA 383

  Fly   578 SAAAF 582
            :|.|:
Mouse   384 AATAY 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	57/100 (57%)
		Homeobox	388..440	CDD:278475	11/60 (18%)
Pax5	NP_032808.1	PAX	16..140	CDD:128645	64/137 (47%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	19..75		18/69 (26%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	94..142		33/47 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	182..218		11/39 (28%)
		Pax2_C	285..389	CDD:289189	29/141 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810