DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and ceh-53

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_500361.3	Gene:	ceh-53 / 182467	WormBaseID:	WBGene00015651	Length:	203	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	63/212 - (29%)
Similarity:	93/212 - (43%)	Gaps:	53/212 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   376 SQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWR 440
            :|:|::.:.||.||.||..||:.||:.|.|..||.|..||.|..:|.|:|||:||||.|||||.|
Worm    23 AQNSEERRVRRLRTAFSENQLELLEEAFLKCQYPDVQQRETLGKQTELAEARIQVWFKNRRAKAR 87

  Fly   441 RHQRVNLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVPVAVPESGQQKQPYPYSTSNMCNTSSS 505
            :.||        :.||.|..|                    ..||.::      ..::.| ....
Worm    88 KRQR--------NESTDSCST--------------------TEESNEE------GDADGC-LKKK 117

  Fly   506 SSNSQPCNTINPGSKMSSKTSSVSSNQHMEEPAAAVATASPTASA-PLSMGGENSAFRAL-PM-- 566
            :.|.....|..||:.:.:.:.|.::            |:.||..| ||:.....:.|.|. |.
Worm   118 AKNETTIITWTPGAALFNSSLSPTT------------TSIPTTPAPPLNFICHQNPFYAYNPYRN 170

  Fly   567 --TLPMPMTLPTASAAA 581
              |:|..:...|.:||:
Worm   171 LNTIPTHLLAATTTAAS 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	30/51 (59%)
ceh-53	NP_500361.3	Homeobox	35..81	CDD:365835	25/45 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810