DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and dsc-1

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_510497.1	Gene:	dsc-1 / 181599	WormBaseID:	WBGene00001096	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	58/236 - (24%)
Similarity:	84/236 - (35%)	Gaps:	78/236 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 ASY----GYAIH----PTHPH-------PYTSFPTWPAHHPLWGAVPLATPPGGGPAGAGGALQP 294
            |||    |.|:|    .::.|       |.|..|...||..  |.:|..:|
Worm    71 ASYYHNLGVALHNHFQMSNQHYLSDFDCPTTVSPISSAHET--GQLPQLSP-------------- 119

  Fly   295 GGSGSSYGSDGNMSS---NPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDS----G 352
                  |...||...   :|::..::....|.:..|:.......:.|:..|:...:|.|:    |
Worm   120 ------YDHIGNQDPHMFSPHAYGNSMIPDNSYFENASRSISAPNVGNSTLNPSLMSSDNAQSCG 178

  Fly   353 SRDSRSPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKL 417
            .|                              ||.||.|:..|...||..|.:||||....::.:
Worm   179 GR------------------------------RRFRTNFTELQSTFLEDSFKESHYPDHKAKKYM 213

  Fly   418 AARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSS 458
            |....:.|.|:.|||.||||||||.:.    :|||.....|
Worm   214 ADFLKIPEDRITVWFQNRRAKWRRKEH----RQRDRTRNES 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	22/51 (43%)
dsc-1	NP_510497.1	Homeobox	184..236	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910