DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and ceh-51

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_507685.1	Gene:	ceh-51 / 180233	WormBaseID:	WBGene00013583	Length:	234	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	49/212 - (23%)
Similarity:	71/212 - (33%)	Gaps:	74/212 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   312 NSSNSNTTHSNGHNTNSGSGCGDSSAGSGRL-----SLPALSPDSGSRDSRSPD----------A 361
            :|||.|..:...:...|.|....:||.:...     ::|:.||.|.|.....|.          |
Worm     2 SSSNYNINNGGDYYPLSSSNLNSTSAITNATVMEYSTMPSSSPGSMSSSPAYPAAYQAPSPCYVA 66

  Fly   362 DANRM-----IDIEGED----------------------SESQDSDQP----------------- 382
            |.|::     :...|.|                      |:...|..|
Worm    67 DPNQLYYQQQLAHNGNDMLVQAHAQAYQAQCFAWFQQQYSQLSPSSFPHPMVAHHAGFIPPPPSF 131

  Fly   383 --------------KFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFS 433
                          |.|..||.||..||..|...|::.....|:.|.||.|...||..::::||.
Worm   132 LHHQHQQHPRAPSEKRRGARTPFSDSQLYALRTRFEQCDTIKVDERRKLGAVIGLSPEQIKIWFQ 196

  Fly   434 NRRAKWRRHQRVNLIKQ 450
            |||.|.|: ::...|||
Worm   197 NRRFKLRK-EKYKQIKQ 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	21/51 (41%)
ceh-51	NP_507685.1	Homeobox	151..204	CDD:365835	21/52 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910