DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and Hoxd10

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_006498852.1	Gene:	Hoxd10 / 15430	MGIID:	96202	Length:	410	Species:	Mus musculus

Alignment Length:	192	Identity:	44/192 - (22%)
Similarity:	75/192 - (39%)	Gaps:	44/192 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 PNSSNSNTTHSNG-----HNTNSGS----------GCGDSSAGSGRLSLPALSPDSGSRDS---- 356
            |.....:.|::.|     :|:..||          |.......:.:|.:.....:|.|...
Mouse   219 PGYFRLSQTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKKMNESASGQEPTKV 283

  Fly   357 ---RSPDA------DANRMIDI--------EGEDSESQDSDQP--------KFRRNRTTFSPEQL 396
               .||:|      |.:.:.::        |.|..|...||.|        ..|:.|..::..|.
Mouse   284 SQVESPEAKGGLPEDRSCLAEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQT 348

  Fly   397 DELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDSPSTSS 458
            .||||||..:.|.....|.:::....|::.:|::||.|||.|.::..|.|.|::..:..|.|
Mouse   349 LELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	18/51 (35%)
Hoxd10	XP_006498852.1	Homeobox	339..393	CDD:365835	18/53 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910