Protein Alignment toe and AgaP_AGAP000063

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_566364.4
• Gene: AgaP_AGAP000063 / 1272212
• VectorBaseID: AGAP000063
• Length: 564
• Species: Anopheles gambiae
• Alignment Length: 596
• Identity: 174/596 - (29%)
• Similarity: 252/596 - (42%)
• Gaps: 148/596 - (24%)

  Fly   104 LGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYDLAQHMLSQQGAVSKLL---- 164
            |||||.||.....              :::.|::||:..|.|..|:::.:....|.|||:|
Mosquito    14 LGGIFVGGRPLPD--------------STRQRIVELAHAGARPCDISRILQVSNGCVSKILGRYY 64

  Fly   165 --GTLRPPGLIGGSKPKVATPTVVSKIEQYKRENPTIFAWEIRERLITEGVCTNATAPSVSSINR 227
              |::||.. ||||||:||||.||:||.|:|...|.|||||||::|:.|.:||....||||||||
Mosquito    65 ETGSIRPRA-IGGSKPRVATPEVVNKISQFKNNCPNIFAWEIRDKLLNERICTPENIPSVSSINR 128

  Fly   228 ILRNRAAERAAAEFARAASYGYAIHPTHPH---------------------PYTSFPTWPAHHPL 271
            :|||.||::   ||::           .||                     .:..:....:...:
Mosquito   129 VLRNLAAQK---EFSK-----------KPHSADALSDDVGGYLQGKSLNDASFIHYKYGDSCRSM 179

  Fly   272 WGAVPL---------ATPPGGGPA---GAGGALQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGH 324
            .||..:         |...|||||   |.||...|||.||. .:|....|:..:.|....|.
Mosquito   180 QGAESVLRINDTYSRAGGGGGGPAAGGGGGGGAVPGGPGSE-STDVKPMSDDGTKNPFAKHC--- 240

  Fly   325 NTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRS--PDADANRMIDIEGEDSESQDSDQPKFRRN 387
            .||..:|.  ..||:|       :|..|...::.  .|.|..|:            |.:.|.:||
Mosquito   241 FTNLDAGV--PGAGTG-------TPGQGGPGTKQVFVDNDTERL------------SLKRKLQRN 284

  Fly   388 RTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQ-----VWFSNRRAKWRRHQRVNL 447
            ||:|:.:|::.|||||:::|||.|.:||:|:::|.|.|||:|     ||||||||||||.:
Mosquito   285 RTSFTVDQIEFLEKEFERTHYPDVFSRERLSSKTNLPEARIQVSYIEVWFSNRRAKWRREE---- 345

  Fly   448 IKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVPVAVPESGQQKQPYPYST----SNMCNTSSSSSN 508
             |||....:..|.:.......:..:...|.|..|...|.......|..:    ||||...|:|:.
Mosquito   346 -KQRSQAVSEGSSSAAAAAAAAAAAAAAVAVQNASISSCSLNLTAPLVSHVYDSNMCVEDSNSNY 409

  Fly   509 SQPCNTINPGSKMSSKTSSVSSNQHMEEP----AAAVA------TASPTASAPLSMGGENSAFRA 563
            ......:.|..:......|.|:..|...|    .||::      .|:|......:.||......|
Mosquito   410 LSKTYPLEPSFQNLDALKSPSAPNHPAAPQQLSPAAMSFKLSFPNANPNGGVGPNNGGGGGGGGA 474

  Fly   564 LPMTLPMPMTLPTASAAAFALSFARQYIAKYMGTPLNLGHGSSPIQAQSGRDHQSEEREYEDEQE 628
                      .|..|||        ..:...:||.....|.|:           |:::...:...
Mosquito   475 ----------APDGSAA--------NLMGPSLGTNAGFPHAST-----------SDDKSLYNHFA 510

  Fly   629 EEEVINVEHDA 639
            .....|:.|.|
Mosquito   511 YSAAANMHHSA 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	50/101 (50%)
		Homeobox	388..440	CDD:278475	31/56 (55%)
AgaP_AGAP000063	XP_566364.4	PAX	7..131	CDD:128645	57/131 (44%)
		Homeobox	285..342	CDD:278475	31/56 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26145
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820