Protein Alignment toe and Pax3

DIOPT Version :9

• Sequence 1: NP_524041.2
• Gene: toe / 39418
• FlyBaseID: FBgn0036285
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_446162.1
• Gene: Pax3 / 114502
• RGDID: 620431
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 550
• Identity: 154/550 - (28%)
• Similarity: 224/550 - (40%)
• Gaps: 168/550 - (30%)

  Fly    87 LSPSTPILTQGAPPAAALGGIFCGGSAAAGPGAAAAAATNLNALASQHRLLELSRFGLRGYDLAQ 151
            |..|||:   |......|||:|..|....            |.:  :|:::|::..|:|...:::
  Rat    27 LEVSTPL---GQGRVNQLGGVFINGRPLP------------NHI--RHKIVEMAHHGIRPCVISR 74

  Fly   152 HMLSQQGAVSKLL------GTLRPPGLIGGSKPK-VATPTVVSKIEQYKRENPTIFAWEIRERLI 209
            .:....|.|||:|      |::| ||.||||||| |.||.|..|||:||||||.:|:||||::|:
  Rat    75 QLRVSHGCVSKILCRYQETGSIR-PGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLL 138

  Fly   210 TEGVCTNATAPSVSSINRILRNR--AAERAAAEFARAASYGYAIHPTHPHPYTSFPTWPAHHPLW 272
            .:.||...|.||||||:||||::  ..|...|:..|..:
  Rat   139 KDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEA-------------------------- 177

  Fly   273 GAVPLATPPGGGPAGAGGALQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSA 337
                                :.....:.:..||.:|...::..|
  Rat   178 --------------------EESEKKAKHSIDGILSERASAPQS--------------------- 201

  Fly   338 GSGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKE 402
                        |.||.....||....|                 |.||:||||:.|||:|||:.
  Rat   202 ------------DEGSDIDSEPDLPLKR-----------------KQRRSRTTFTAEQLEELERA 237

  Fly   403 FDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNLIKQRDS------PSTSSSPT 461
            |:::|||.:.|||:||.|..|:|||||||||||||:||:....|.:...:.      |.|:....
  Rat   238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTL 302

  Fly   462 PLVNPVVSPVSPIPVPVPVAVPESG-QQKQPYPYSTSNM----CNTSSSSS-------------- 507
            |......:...|..:|..|:.|.|. .:.||.|.||.:.    .|..|||:
  Rat   303 PTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYT 367

  Fly   508 -----NSQPCNTINP--GSKMSSKTSSVSSNQ----HMEE------PAAAVATASPTASAPLSMG 555
                 .|.|.|.:||  |:.:|.:...:.:|.    |..:      |.......:.|.||..|..
  Rat   368 DSFVPPSGPSNPMNPAIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQR 432

  Fly   556 GEN-SAFRALPMTLPMPMTLPTASAAAFAL 584
            .|: ....:||.:  .|...||.|...:::
  Rat   433 LEHMKNVDSLPTS--QPYCPPTYSTTGYSM 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362	50/102 (49%)
		Homeobox	388..440	CDD:278475	34/51 (67%)
Pax3	NP_446162.1	PAX	34..159	CDD:128645	57/139 (41%)
		MFAP1	164..>286	CDD:336570	53/217 (24%)
		Homeobox	222..276	CDD:333795	35/53 (66%)
		Pax7	347..391	CDD:289156	11/43 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810