DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and Rax

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_446130.1	Gene:	Rax / 114213	RGDID:	620371	Length:	342	Species:	Rattus norvegicus

Alignment Length:	336	Identity:	101/336 - (30%)
Similarity:	134/336 - (39%)	Gaps:	105/336 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 PGGGPAGAGGAL--------QPGGSGSSYGS----------DGNMSSNPNSSNSNTTHSNGHNTN 327
            ||..||.|.|:.        .||||.|...|          ||.:.:.|...:|..:........
  Rat     4 PGCPPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKEDGILDTFPAERSSRGSKERDPRLG 68

  Fly   328 SGSGCGDSSAGSGRLSLPALSPDSGSRDSRSPDADANRMI--DIEGE--------------DSES 376
            :.|.|..:.||....|.|| :|      ...|:.:|.|..  ..:||              ||:.
  Rat    69 ARSACPKAPAGGSESSPPA-AP------GLVPEFEATRPCYPKEQGEARPSPGLPVGPAAGDSKL 126

  Fly   377 QDSDQP---KFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAK 438
            .:.::|   |.|||||||:..||.|||:.|:|||||.|.:||:||.:..|.|.||||||.|||||
  Rat   127 SEEEEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAK 191

  Fly   439 WRRHQR--VNLIKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVPVAVPESGQQKQPYPYSTSNMCN 501
            |||.::  |:.:|.:|||..|.|.:|          |.....|:..|.||
  Rat   192 WRRQEKLEVSSMKLQDSPLLSFSRSP----------PSSALAPLGGPGSG--------------- 231

  Fly   502 TSSSSSNSQPCNTINPGSKMSSKTSSVSSNQHMEEPAAAVATASPTASAPLSMGGENSAFRALPM 566
                   |.|     |||.:                     ...|....||. ||..:|.::||.
  Rat   232 -------SGP-----PGSAL---------------------PLEPWLGPPLP-GGGATALQSLPG 262

  Fly   567 TLPMPMTLPTA 577
            ..|....||.:
  Rat   263 FGPPGQGLPAS 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	33/51 (65%)
Rax	NP_446130.1	Octapeptide motif	33..40		1/6 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	49..141		21/98 (21%)
		Homeobox	141..193	CDD:278475	33/51 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	209..295		25/124 (20%)
		OAR	316..331	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	319..332
		Nuclear localization signal. /evidence=ECO:0000255	325..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910