DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and Hoxc11

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001020013.1	Gene:	Hoxc11 / 109663	MGIID:	96193	Length:	304	Species:	Mus musculus

Alignment Length:	218	Identity:	53/218 - (24%)
Similarity:	83/218 - (38%)	Gaps:	58/218 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 SYGYAIHPTHPHP-----YTS----------FPTWPAHHPLWGAVPLATPPGGGPAGAGGALQ-P 294
            |||...||:.||.     |:|          |..:..:....|....|.||..|...|.|..: |
Mouse   120 SYGGHHHPSAPHAAPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDAPAEPPCSGKGEAKGEPEAP 184

  Fly   295 GGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCGDSSAGSGRLSLPALSPDSGSRDSRSP 359
            ..||.:..::....:.....|:|                .||:||...:  ...|..|:    :|
Mouse   185 PASGLASRAEAGAEAEAEEENTN----------------PSSSGSSHSA--TKEPAKGA----AP 227

  Fly   360 DADANRMIDIEGEDSESQDSDQPKFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALS 424
            :|                    |:.|:.|..:|..|:.|||:||..:.|.....|.:|:....|:
Mouse   228 NA--------------------PRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLT 272

  Fly   425 EARVQVWFSNRRAKWRRHQRVNL 447
            :.:|::||.|||.|.::..|..|
Mouse   273 DRQVKIWFQNRRMKEKKLSRDRL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	19/51 (37%)
Hoxc11	NP_001020013.1	DUF3528	42..178	CDD:403310	15/57 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..237		21/111 (19%)
		Homeobox	235..289	CDD:395001	19/53 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000