DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toe and Rhox9

DIOPT Version :9

Sequence 1:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_076383.1	Gene:	Rhox9 / 104384	MGIID:	1890128	Length:	227	Species:	Mus musculus

Alignment Length:	212	Identity:	54/212 - (25%)
Similarity:	80/212 - (37%)	Gaps:	46/212 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   283 GGPAGAGGA--------------LQPGGSGSSYGSDGNMSSNPNSSNSNTTHSNGHNTNSGSGCG 333
            ||.|...||              |..||.....|:.|.::....:.......|.......|...|
Mouse    28 GGNAVVSGAGEEGIDKKELVMSGLAQGGLDQGEGAQGEVAGGEQAQEEPAPLSPAQEATGGEEEG 92

  Fly   334 DSSAG--SGRLSLPALSPDSGSRDSRSPDADANRMIDIEGEDSESQDSDQ-----PKFRRN---- 387
            ::..|  .||          .:.|..|...|.|  |..||.::..|...|     |:..||
Mouse    93 ENKEGEMEGR----------HAGDGASGPEDDN--IQEEGGENIDQQPPQQEAAIPEGMRNPQAG 145

  Fly   388 ---------RTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQ 443
                     ||.|:..||.:||:.|.::.:|.:..|..||....:.|:.||.||..|||.:|||.
Mouse   146 NYLAHQRTRRTRFTHSQLRDLERLFQENRFPSLRVRRDLARWMGVDESDVQEWFKMRRALFRRHS 210

  Fly   444 RVNLIKQRDSPSTSSSP 460
            |:.:..:....:.::||
Mouse   211 RLMMFCELPPITENNSP 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	20/51 (39%)
Rhox9	NP_076383.1	Homeobox	154..207	CDD:278475	20/52 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910